DRSC/TRiP Functional Genomics Resources

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Protein Alignment RNF112 and si:ch211-209n20.1

DIOPT Version :10

Sequence 1:XP_006721634.1 Gene:RNF112 / 7732 HGNCID:12968 Length:639 Species:Homo sapiens
Sequence 2:XP_021331173.2 Gene:si:ch211-209n20.1 / 100149641 ZFINID:ZDB-GENE-070705-98 Length:378 Species:Danio rerio


Alignment Length:416 Identity:83/416 - (19%)
Similarity:148/416 - (35%) Gaps:91/416 - (21%)


- Green bases have known domain annotations that are detailed below.


Human   135 EPLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLNHLLQGLPGLESG 199
            :|:.|:..::.|.|.::..|: :.|:.   ...||.::||:|...:|||:|:||    |.|.::|
Zfish     3 KPVCLINTDSDGKLCVQPAAL-QVLQQ---IQQPVVVVAVVGLYRTGKSYLMNH----LAGKQTG 59

Human   200 EGGRPRGGEASLQGCRWGANGLARGIWMW--SHPFLLGKEGKKVAVFLVDT---GDAMSPELSRE 259
            ..   .||....:         .:|||||  .||...|     ..:.|:||   ||....:...:
Zfish    60 FA---LGGTIESK---------TKGIWMWCVPHPTKTG-----TTLVLLDTEGLGDVEKGDSKHD 107

Human   260 TRIKLCALTTMLSSYQILSTSQELKDTDLDYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHPN 324
            |.| .| |..:|||..:.::|..:.:..::.|:....:.|       .:.::..|..|.||:...
Zfish   108 TNI-FC-LAVLLSSTLVYNSSGTIDNRAIEELQYVTELTE-------CIKVKSSDEDVDDSTEFV 163

Human   325 KAGQGHVGNIFQSTPLAASQRLSGRYPKVQELLQ---------GKR----------------ARC 364
            |.....:.::...|   ..:::.|:.....|.|:         .|:                .|.
Zfish   164 KFFPSFIWSVRDFT---LERKIDGKDATEDEYLEFALKLKPGTSKKITSFNLPRECIQKFFPTRT 225

Human   365 CL---LPAPGRRRMNQGHASPGDTDDDFRHLLGAYVSDVLSAAPQHAKSRCQGYWNEGRAVARGD 426
            |.   .|....:.......||.|...:|..:               .|..|:..:::.......|
Zfish   226 CFTFPFPTAPEKMSTLESLSPADLSTEFLEV---------------TKRFCKFVFDKSEVKRLKD 275

Human   427 RRLLTGQQLAQEIKNLSGWMGRTGPGFTSP--DEMAAQLHDLRKVEAAKREFEEYVRQQDVATKR 489
            ...:||:.|.    ||:.....|......|  :.....:..:..|.|.:...|.|.|..:.....
Zfish   276 GHTVTGRVLG----NLTKMYVNTISSGAVPCLENAVIAMAQIENVAATQEGLEVYQRGMEKVKCS 336

Human   490 IFSALRVLPDTMRNLLSTQKDAILAR 515
            ....|..:....:.|.|....|.:||
Zfish   337 FPLELEQVSSEHQRLSSKATQAFMAR 362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNF112XP_006721634.1 RING-HC_RNF112 53..104 CDD:438200
GBP 163..402 CDD:206650 56/271 (21%)
si:ch211-209n20.1XP_021331173.2 GBP 13..273 CDD:460516 62/311 (20%)
GBP_C 281..>376 CDD:293879 17/86 (20%)
Blue background indicates that the domain is not in the aligned region.

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