DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ZNF165 and CG17359

DIOPT Version :9

Sequence 1:NP_001363420.1 Gene:ZNF165 / 7718 HGNCID:12953 Length:485 Species:Homo sapiens
Sequence 2:NP_648679.1 Gene:CG17359 / 39549 FlyBaseID:FBgn0036396 Length:339 Species:Drosophila melanogaster


Alignment Length:361 Identity:88/361 - (24%)
Similarity:134/361 - (37%) Gaps:81/361 - (22%)


- Green bases have known domain annotations that are detailed below.


Human   129 RGTDEAVLQVQAHEHGQEIFQKKVSPPGPALNVKLQPVE-TKAHFDSSEPQLLW-DCDNESENS- 190
            |...:.:|.:....:..   ..:|....|.|...|:... ...|.:...||.:. :|.....|: 
  Fly    11 RDESDCLLDIYTEPYAS---SNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECAEAVRNAY 72

Human   191 ----------------RSMPK--------LEIFEKIESQRIISGRISGYISEASGESQDICKSAG 231
                            |.|.|        |.|.:.||.|..:|...:|...|.   |:.:.....
  Fly    73 RLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPET---SEPLLVELV 134

Human   232 RVKRQWEKESGESQRLSSAQDEGFGKILTHKNTVRGEIISHDGCERRLNLNS--------NEFTH 288
            :||....:....|..|....:....:..:...|      .|:..:||....|        :|..|
  Fly   135 QVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKT------PHNKSKRRARSYSDNDSWSPDSELEH 193

Human   289 QKSCKHGTCDQSFKWNSDFINHQIIYAGEKNHQYGKSFKSPKLAKHAAVFSGDKTHQCNECGKAF 353
            :        |....||:.              :.||..:.|            ..::|..|.::|
  Fly   194 E--------DDDKIWNAS--------------KRGKPKRVP------------GPYRCKLCTQSF 224

Human   354 RHSSKLARHQRIHTGERCYECNECGKSFAESSDLTRHRRIHTGERPFGCKECGRAFNLNSHLIRH 418
            .....|..|.|||||||.|:|:.|.:|||:..:|..|.|.|||||||||..|.:.|.....|..|
  Fly   225 TQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVH 289

Human   419 QRIHTREKPYECSECGKTFRVSSHLIRHFRIHTGEK 454
            .|.||.|:|::||:|.::|:..:.|.:|...||..|
  Fly   290 TRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGK 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZNF165NP_001363420.1 SCAN 45..157 CDD:128708 3/27 (11%)
C2H2 Zn finger 297..314 CDD:275368 3/16 (19%)
zf-C2H2 344..366 CDD:333835 6/21 (29%)
C2H2 Zn finger 346..366 CDD:275368 6/19 (32%)
COG5048 370..>431 CDD:227381 28/60 (47%)
zf-C2H2 372..394 CDD:333835 9/21 (43%)
C2H2 Zn finger 374..394 CDD:275368 8/19 (42%)
C2H2 Zn finger 402..422 CDD:275368 6/19 (32%)
COG5048 426..>479 CDD:227381 10/29 (34%)
C2H2 Zn finger 430..450 CDD:275368 6/19 (32%)
C2H2 Zn finger 458..478 CDD:275368
CG17359NP_648679.1 zf-AD 6..88 CDD:285071 11/79 (14%)
zf-C2H2 215..237 CDD:278523 6/21 (29%)
C2H2 Zn finger 217..237 CDD:275368 6/19 (32%)
zf-H2C2_2 229..254 CDD:290200 14/24 (58%)
C2H2 Zn finger 245..265 CDD:275368 8/19 (42%)
zf-H2C2_2 257..282 CDD:290200 14/24 (58%)
C2H2 Zn finger 273..293 CDD:275368 6/19 (32%)
zf-H2C2_2 286..310 CDD:290200 11/23 (48%)
C2H2 Zn finger 301..321 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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