DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZBTB16 and Kr-h1

DIOPT Version :9

Sequence 1:NP_001018011.1 Gene:ZBTB16 / 7704 HGNCID:12930 Length:673 Species:Homo sapiens
Sequence 2:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster


Alignment Length:475 Identity:127/475 - (26%)
Similarity:184/475 - (38%) Gaps:88/475 - (18%)


- Green bases have known domain annotations that are detailed below.


Human   243 TEMMQVDEVPSQDSPGAAESSISGGMGDKVEERGKEGPGTPTRSSVITSARELHYGREESAE--- 304
            ||::.:.:.|::                .|..:......:.|...|..||.:|....|:|::   
  Fly    27 TELLDISKSPAK----------------AVAVKKSPAKDSATTKMVYYSANQLLIKTEQSSQAQF 75

Human   305 --QVPPPAEAGQAPTGRPEHPAPPPEKHLGIYS---------------------------VLPNH 340
              |||||..|.....|....|:...::|..:..                           .:..|
  Fly    76 CLQVPPPLTATTTSVGLGVPPSGGQQEHFELLQTPQQRQMQLQLQDQHQQEQQQFVSYQLAIQQH 140

Human   341 KADAVLSMPSSVTSGLHVQPALAVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESRTIGEQ 405
            :.........|:|:........|..:.....||......:..::          .|..:.....:
  Fly   141 QKQQQQQQHESITNAAPTAAPSAQRIKTEPVGGFPASAAVVSQV----------RKPSASKPQFK 195

Human   406 CSVCGVELPDNEAVEQHRKLHSGMKTYGCELCGKR-------------FLDSLRLRMHL------ 451
            |..||:......|...|.|.||  |.....|.|..             .|:...|.:.:      
  Fly   196 CDQCGMTFGSKSAHTSHTKSHS--KNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTI 258

Human   452 --LAH-SAGAKAFVCDQCGAQFSKEDALETHRQTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHA 513
              ||: :|||..:.|:.|...|:....|..|.:|||| :....|..|.|.|..:..||.|..:|.
  Fly   259 KPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTG-ERPFECEFCHKLFSVKENLQVHRRIHT 322

Human   514 GVRSYICSECNRTFPSHTALKRHLRSHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYEC-- 576
            ..|.|.|..|.|.|.....|.||:|.|||:.|::|..|...|.....|..|.|.|||||||:|  
  Fly   323 KERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPE 387

Human   577 NGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIK-HLRTHNGASPYQCTICTEYCP 640
            .||||.|:...||:.|.|.||||||:.|.:|. |...|:.::| |...|.|:..|:||||.|...
  Fly   388 PGCGKGFTCSKQLKVHSRTHTGEKPYHCDICF-RDFGYNHVLKLHRVQHYGSKCYKCTICDETFK 451

Human   641 SLSSMQKHMKGHKPEEIPPD 660
            :...|:.|:||| ..|:|.|
  Fly   452 NKKEMEAHIKGH-ANEVPDD 470

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZBTB16NP_001018011.1 BTB 25..125 CDD:306997
Herpes_ICP4_C 177..>327 CDD:332854 19/88 (22%)
Interaction with RUNX1T1. /evidence=ECO:0000269|PubMed:10688654 200..300 9/56 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 215..236
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..332 18/87 (21%)
C2H2 Zn finger 406..426 CDD:275368 6/19 (32%)
C2H2 Zn finger 434..454 CDD:275368 5/40 (13%)
COG5048 <448..622 CDD:227381 71/185 (38%)
C2H2 Zn finger 463..483 CDD:275368 5/19 (26%)
C2H2 Zn finger 492..512 CDD:275368 7/19 (37%)
C2H2 Zn finger 520..540 CDD:275368 8/19 (42%)
C2H2 Zn finger 548..568 CDD:275368 6/19 (32%)
C2H2 Zn finger 576..596 CDD:275368 10/21 (48%)
C2H2 Zn finger 604..624 CDD:275368 6/20 (30%)
C2H2 Zn finger 632..652 CDD:275368 8/19 (42%)
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 6/19 (32%)
COG5048 <270..420 CDD:227381 62/151 (41%)
zf-C2H2 271..293 CDD:278523 5/21 (24%)
C2H2 Zn finger 273..293 CDD:275368 5/19 (26%)
zf-H2C2_2 286..309 CDD:290200 9/23 (39%)
C2H2 Zn finger 301..321 CDD:275368 7/19 (37%)
zf-H2C2_2 313..338 CDD:290200 10/24 (42%)
C2H2 Zn finger 329..349 CDD:275368 8/19 (42%)
zf-H2C2_2 344..366 CDD:290200 10/21 (48%)
C2H2 Zn finger 357..377 CDD:275368 6/19 (32%)
zf-H2C2_2 370..396 CDD:290200 16/25 (64%)
C2H2 Zn finger 385..407 CDD:275368 10/21 (48%)
zf-H2C2_2 400..424 CDD:290200 12/24 (50%)
C2H2 Zn finger 415..435 CDD:275368 6/20 (30%)
zf-C2H2 441..463 CDD:278523 9/21 (43%)
C2H2 Zn finger 443..463 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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