DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZNF222 and CG12391

DIOPT Version :9

Sequence 1:NP_001123468.1 Gene:ZNF222 / 7673 HGNCID:13015 Length:491 Species:Homo sapiens
Sequence 2:NP_610639.1 Gene:CG12391 / 36170 FlyBaseID:FBgn0033581 Length:587 Species:Drosophila melanogaster


Alignment Length:211 Identity:55/211 - (26%)
Similarity:90/211 - (42%) Gaps:34/211 - (16%)


- Green bases have known domain annotations that are detailed below.


Human   126 TTISNSQLFEQDDNPSQIKARLSTVHTREKPF-QGENCKQFFSDVSFFDLPQQLYSGEKSHT--- 186
            ||.::|...:.||:..:.|........|:||. :|.:     ||.......::.|....:.:   
  Fly   356 TTSADSDSADSDDSEKEKKKPGPRGRPRKKPLKRGTD-----SDGEPSSAQKKKYQPSSTASVGP 415

Human   187 --CDECGKSFCYISALHIHQRVHMGVKCYKCDVCGKEFSQSSRLQTHQRVHTGEKP-FKCEQCGK 248
              |..|..:|....:..:|::.|..:: :.|.:|||:|......:||.:.|..|:. |:||.|.|
  Fly   416 FECPNCDLTFSRKQSYVLHRKTHERIE-HACPICGKKFKVEWAYKTHMQRHEQERAHFRCELCPK 479

Human   249 GFRCRSALKVHCKLHMREKP--YNCEKCGKAFMHNFQLQKHH------------RIHTGEKPFKC 299
            .||.|:.||.|......|..  |.|::|.:.|:...:||:|.            ||...:..||.
  Fly   480 IFRLRAELKHHMAQRHDEHGFIYECKRCQRTFLTQQRLQRHQAVGCQRHKEDSVRIKEEQSRFKQ 544

Human   300 EICGKSFCLRSSLNRH 315
            |       .||..:||
  Fly   545 E-------SRSKDDRH 553

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZNF222NP_001123468.1 KRAB 17..76 CDD:214630
KRAB 17..56 CDD:279668
C2H2 Zn finger 160..179 CDD:275368 2/18 (11%)
COG5048 <183..315 CDD:227381 40/151 (26%)
C2H2 Zn finger 187..207 CDD:275368 4/19 (21%)
C2H2 Zn finger 215..235 CDD:275368 7/19 (37%)
zf-H2C2_2 228..252 CDD:290200 10/24 (42%)
C2H2 Zn finger 243..263 CDD:275368 10/19 (53%)
C2H2 Zn finger 271..291 CDD:275368 7/31 (23%)
zf-H2C2_2 284..306 CDD:290200 8/33 (24%)
C2H2 Zn finger 331..347 CDD:275368
C2H2 Zn finger 355..375 CDD:275368
zf-H2C2_2 367..390 CDD:290200
C2H2 Zn finger 383..403 CDD:275368
C2H2 Zn finger 411..431 CDD:275368
C2H2 Zn finger 439..459 CDD:275368
CG12391NP_610639.1 zf-AD 240..313 CDD:285071
zf-C2H2 416..438 CDD:278523 4/21 (19%)
C2H2 Zn finger 418..438 CDD:275368 4/19 (21%)
zf-C2H2 443..465 CDD:278523 7/21 (33%)
C2H2 Zn finger 445..465 CDD:275368 7/19 (37%)
C2H2 Zn finger 474..491 CDD:275368 9/16 (56%)
C2H2 Zn finger 504..521 CDD:275368 5/16 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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