Protein Alignment CA5A and CAH16

DIOPT Version :10

• Sequence 1: NP_001730.1
• Gene: CA5A / 763
• HGNCID: 1377
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_001287620.1
• Gene: CAH16 / 50101
• FlyBaseID: FBgn0040628
• Length: 286
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 84/258 - (32%)
• Similarity: 123/258 - (47%)
• Gaps: 44/258 - (17%)

Human    61 GTRQSPINIQWRDS------------VYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEAS 113
            |..||||.:..|.:            .|....:|          .||.|.|:  .:..|....::
  Fly    42 GKHQSPILLDSRTARKWVLPGITFWHYYRLLKRP----------FYIRNNGH--SISLDIPVTSN 94

Human   114 G----ISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGE 174
            |    |:||.|:..|.....|||||:....||||.::...:.||:|:||.|. ||:|..:||..:
  Fly    95 GRKPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAEIHIVHRNE-KYRNIAQAVRQK 158

Human   175 NGLAVIGVFL----KLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCW-----DYWTY 230
            :||||:.:.:    |..|....|.||::.:..:..:|:.|.:  |..|:|.....     |::||
  Fly   159 DGLAVVAIMVAIVRKDNAKSTPLSRLMEAVVRVPIEDSNATV--FGQSSLDQLIGGVSHRDFFTY 221

Human   231 AGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVW 293
            .||||||...|:||||:..|...|..|.:|.| .||....|..   ::||||.:|.|.||.|:
  Fly   222 EGSLTTPLCDETVTWIVFTETTTVTMSSVSKF-WLLRDHWGHR---LINNYRIVQDLNNRTVF 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CA5A	NP_001730.1	alpha_CA_V	61..296	CDD:239392	84/258 (33%)
CAH16	NP_001287620.1	Carb_anhydrase	33..281	CDD:459707	84/258 (33%)