Protein Alignment CA5A and CAH6

DIOPT Version :10

• Sequence 1: NP_001730.1
• Gene: CA5A / 763
• HGNCID: 1377
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_001097987.1
• Gene: CAH6 / 43701
• FlyBaseID: FBgn0039838
• Length: 298
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 81/252 - (32%)
• Similarity: 130/252 - (51%)
• Gaps: 32/252 - (12%)

Human    61 GTRQSPINIQWRDSVYDPQLKPLRVSYEA--ASCLYIWNTGYLFQVEFDDATEASG----ISGGP 119
            |.|||||::..:.|:..|..:.:..:|:.  ...|.:.|.|:...||..:.  |:|    |:||.
  Fly    46 GERQSPISLNVQKSLIVPLPRIVFGNYDVKLRGPLTLLNNGHTAHVEIPET--ANGNKPFITGGL 108

Human   120 LENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFL 184
            |:..:..:.||||||:.:..||||:::...:..|:|:||.|. ||.:..||...::|:|||||.|
  Fly   109 LKGRFVAEAFHFHWGSPSSRGSEHSINQQRFDVEMHIVHRNE-KYGDIDEAKNKKDGIAVIGVML 172

Human   185 KLGAHHQT----LQRLVDILPEIKHKDARAAMRPFDPSTLL---------PTCWDYWTYAGSLTT 236
            |:..:...    |.:::..||.:...:|:..:    |..|.         |.  |::||.|||||
  Fly   173 KIVKNPNRIFPGLSKVMSALPRVTKYNAKTTI----PGGLSLGQMLGNVNPR--DFFTYRGSLTT 231

Human   237 PPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVW 293
            |...:||||.:..:.:.|..|.:|.|..|..|    |...::||:|.:||...|.|:
  Fly   232 PLCEQSVTWTVFSQVLPVPYSSVSKFWKLRDS----EGHRLINNFRDIQPRNGRPVF 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CA5A	NP_001730.1	alpha_CA_V	61..296	CDD:239392	81/252 (32%)
CAH6	NP_001097987.1	Carb_anhydrase	26..287	CDD:459707	81/252 (32%)