Protein Alignment CA5A and CAH9

DIOPT Version :10

• Sequence 1: NP_001730.1
• Gene: CA5A / 763
• HGNCID: 1377
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_651535.1
• Gene: CAH9 / 43264
• FlyBaseID: FBgn0039486
• Length: 311
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 92/315 - (29%)
• Similarity: 149/315 - (47%)
• Gaps: 59/315 - (18%)

Human     8 KTSAF---SFLVEQMWAPLWSRSM--------RPG--RWCSQRS-CAWQTSNNTLHPLWTVPVSV 58
            |.:||   |||:     ..||:::        .|.  ||..... ||.:|.:         |:::
  Fly     2 KLTAFLEASFLL-----ICWSQAVSSHVFGYSEPNQRRWARHHGHCAGKTQS---------PIAI 52

Human    59 PGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFD--DATEASG-----IS 116
            . .:|.:.|::...|.:....|.|..        |.:.|.|:...:...  :.||...     |.
  Fly    53 T-TSRTTAIHMPAVDMIGYHNLLPYP--------LKMINNGHTVSITIPKVNVTEVGEDFLPYIR 108

Human   117 GGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIG 181
            |..|...:.::..|||||..|..||||.::...|..|:|:||.|. ||....||:...:|.||:|
  Fly   109 GAKLPGEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHIVHRNK-KYATIGEALNHPDGAAVLG 172

Human   182 VFLKL----GAHHQTLQRLVDILPEIKHKDARAAMR-PFDPSTLLP--TCWDYWTYAGSLTTPPL 239
            .|..|    ||...|:.|.:.::.:...:   |.:. .|..|:|:.  ....::||.|||||||.
  Fly   173 FFFNLDEDEGAGLVTINRHLHLIADANQE---ATLNVTFSLSSLIAGVDVDKFYTYKGSLTTPPC 234

Human   240 TESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWA 294
            :|:||||:..:|:.::|.|:|.||.|    ...::..:|:|:|.|||:.||:::|
  Fly   235 SEAVTWILFPDPIPISPKQISRFRQL----SDTQDGALVDNFRTLQPVGNRRIFA 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CA5A	NP_001730.1	alpha_CA_V	61..296	CDD:239392	77/248 (31%)
CAH9	NP_651535.1	Carb_anhydrase	31..286	CDD:459707	83/281 (30%)