Protein Alignment CA5A and CAH1

DIOPT Version :10

• Sequence 1: NP_001730.1
• Gene: CA5A / 763
• HGNCID: 1377
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_523561.1
• Gene: CAH1 / 34786
• FlyBaseID: FBgn0027844
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 107/258 - (41%)
• Similarity: 148/258 - (57%)
• Gaps: 14/258 - (5%)

Human    45 NNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLK--PLRVSYEAASCLYIWNTGYLFQVEFD 107
            |...|  |........|.||||::|....:....:|.  ||:..|.......:.|.||.::|:.:
  Fly    11 NGPAH--WAKEYPQASGHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKSLVNPGYCWRVDVN 73

Human   108 DATEASGISGGPL-ENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAV 171
            .|.  |.::|||| :..::|:|||.|||..:..||||||||.:|..||||||||:.||:::.||.
  Fly    74 GAD--SELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWNTTKYKSFGEAA 136

Human   172 VGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAM-RPFDPSTLLPTCWDYWTYAGSLT 235
            ...:||||:|||||.|.||..|.::..:|..:.||..|..: :..||..|||....||||.||||
  Fly   137 AAPDGLAVLGVFLKAGNHHAELDKVTSLLQFVLHKGDRVTLPQGCDPGQLLPDVHTYWTYEGSLT 201

Human   236 TPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEE------EKMMVNNYRPLQPLMNRKV 292
            |||.:|||.||:.|.|:||:..||:|.|.|....:.||      ...::||:||..||..|::
  Fly   202 TPPCSESVIWIVFKTPIEVSDDQLNAMRNLNAYDVKEECPCNEFNGKVINNFRPPLPLGKREL 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CA5A	NP_001730.1	alpha_CA_V	61..296	CDD:239392	104/242 (43%)
CAH1	NP_523561.1	Carb_anhydrase	11..265	CDD:459707	107/258 (41%)