Protein Alignment Atp11b and CG33298

DIOPT Version :9

• Sequence 1: NP_083846.2
• Gene: Atp11b / 76295
• MGIID: 1923545
• Length: 1175
• Species: Mus musculus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1307
• Identity: 408/1307 - (31%)
• Similarity: 607/1307 - (46%)
• Gaps: 279/1307 - (21%)

Mouse    20 RTIYIANRFPQNGLYTPQK------FIDNRIISSKYTIWNFVPKNLFEQFRRVANFYFLIIFLVQ 78
            ||:...:..|..   ||::      |:.|:|.::|||:.:|:||||.|||.||||.||:.|.|:.
  Fly   228 RTVVPNHTVPPK---TPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLN 289

Mouse    79 LMIDTPTSPITSG-------LPLFFVITVTAIKQGYEDWLRHNSDNEVNGAP--VYVVRSGGLVK 134
            .:      |..|.       :|:.||:.|||:|..:||..|..||..:|...  ||...:....|
  Fly   290 WV------PEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKK 348

Mouse   135 TRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVSVPETAVLQTVA 199
            .:.:.:||||||.::.:|..|||::||.:....|.|::.|..||||||||....|.....:|::.
  Fly   349 VKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIF 413

Mouse   200 NLDSLIAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGM 264
            .....::.:|...|...||||.|.:|  ....|.| |:..|.||||.:|||||..|.|:.||.|.
  Fly   414 VPSKFVSRVEADAPTTKLYRFHGALI--HPTGERV-PISTECLLLRESRLKNTDYIEGIVVYAGH 475

Mouse   265 ETKMALNYKSKSQKRSAVEKSMNTFLIIYLIILISEAIISTILKYTWQAE-EKWDEPWY--NQKT 326
            |||..||......|||.||:.||..:|..:|||:...::..|....|.:. ..:..|:.  |:.|
  Fly   476 ETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLT 540

Mouse   327 EHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNT 391
            .:..:       :..|..::|:...:||:|||||:|:.|.|..|.|..::||:..|::::.:...
  Fly   541 ANMES-------MWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRA 598

Mouse   392 SDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGLKY-------QEINGKLVPEGPSPDSTEGE 449
            .::.|||||::::|||||||||||:|.||.|.:||..|       ::|..|  |..|:|
  Fly   599 MNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSK--PGAPAP------ 655

Mouse   450 VPFLGSLSHLSNSAHLTATSLRTSPESETELIKEHDLFFKAVSLCHTV----------------- 497
             |.:.:.:..|:.|.||..:..| |.::.  |:|   |...:::|:||
  Fly   656 -PLIPNDNLNSDMAQLTQGTYLT-PHAQR--IQE---FLVVLAICNTVIVGAAPHRDMMNASGII 713

Mouse   498 ---QISN---------------------VQTDGIGDGP--------------------------- 511
               ||.|                     ..|..|.:||
  Fly   714 EVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSP 778

Mouse   512 ------------WQPNLAPAQLE------------------------------------------ 522
                        .||.|:|....
  Fly   779 PPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSI 843

Mouse   523 --------------------------------YYASSPDEKALVEAAARAGIIFVGISEETMEVK 555
                                            |.|.||||.|||.||.......:..|...:.|.
  Fly   844 ATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVS 908

Mouse   556 --VLGRLERYKLLHILEFDSDRRRMSVIV-QAPSGEKLLFAKGAESSILPKCI--------GGEI 609
              :.|....|::|.:|.|||.|:.||::| |..|.|.:|:.|||:|||:|..:        |...
  Fly   909 MPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILR 973

Mouse   610 AKTRIHVDEFALKGLRTLCIAYRQFTAKEYEDVDRRLFEARTALQHREEKLADAFQYIEKDLILL 674
            .:|:..:|.:|.:|||.|.:|.|...:.:|.|...|..|...:|::||.:|.|:|..:|.:|.||
  Fly   974 EQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLL 1038

Mouse   675 GATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELI------- 732
            |||.:||||||.|.|||.:|..|||.||||||||.|||::::.|...|.:.|.::.|.
  Fly  1039 GATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAA 1103

Mouse   733 ------------NQKSDS--GCAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKL---FM 780
                        |.|:.|  |..:.||:.          |..|||||.:|:..|....||   |:
  Fly  1104 ETAINFYLTDMENDKTTSTLGYGQSLRKK----------QRALVVDGKTLTFILDPKSKLILPFL 1158

Mouse   781 EVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPI-TLAVGDGANDVSMIQEAHVGIGIMGKEGRQ 844
            .:.:.|::|||||..|||||.:::::|  .|..: |||:|||||||||||.|.||:||.|:||.|
  Fly  1159 RLSKRCASVLCCRSTPLQKAYLVKVVK--EELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQ 1221

Mouse   845 AARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDS 909
            |...:|:.:.||::|.:||..||::.|.|::.::.||||||..|:...|.||.||.||.|.:.|.
  Fly  1222 AVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQ 1286

Mouse   910 VYLTLYNICFTSLPVLIYSLVEQHIDPHVLQSKPTLYRDISKNGLLSI--KAFLYWTVL---GFS 969
            :||.|||:.|||||.|...:.::.:...:|...|.||    |||.|.:  :...:|.:|   .:.
  Fly  1287 MYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLY----KNGRLGVAYRPHDFWLILLDALYQ 1347

Mouse   970 HAFIFFFGSYFLVGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGS 1034
            ...|||.........|.         |.|.|||.:....:....|..|:|...||.::.|....|
  Fly  1348 SLVIFFVALCAYAESDV---------GIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS 1403

Mouse  1035 IIFYFIFSLFYGGILWPFLGSQNMYFVFIQLLSSGSAWFAILLMVVTCLFIDVVKKVFDRQLHPT 1099
            :..:::|::.|..:.....|.::.|:|.....:|...|..|:|..|..:...::.......|.|.
  Fly  1404 LGSFYLFAIVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPD 1468

Mouse  1100 STEKAQL 1106
            .:.|..|
  Fly  1469 DSTKVIL 1475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp11b	NP_083846.2	PhoLip_ATPase_N	21..89	CDD:292826	27/73 (37%)
		ATPase-Plipid	39..1105	CDD:273734	402/1279 (31%)
		E1-E2_ATPase	96..>180	CDD:278548	32/85 (38%)
		Cation_ATPase	493..604	CDD:289987	49/267 (18%)
		HAD_like	628..867	CDD:304363	108/263 (41%)
		PhoLip_ATPase_C	846..1099	CDD:292829	74/257 (29%)
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	24/55 (44%)
		ATPase-Plipid	250..1473	CDD:273734	401/1278 (31%)
		E1-E2_ATPase	302..>394	CDD:278548	33/91 (36%)
		Cation_ATPase	<880..965	CDD:289987	33/84 (39%)
		HAD_like	<1177..1240	CDD:304363	32/64 (50%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	74/257 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820