Protein Alignment CA4 and CAH1

DIOPT Version :9

• Sequence 1: XP_005257696.1
• Gene: CA4 / 762
• HGNCID: 1375
• Length: 336
• Species: Homo sapiens
• Sequence 2: NP_523561.1
• Gene: CAH1 / 34786
• FlyBaseID: FBgn0027844
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 321
• Identity: 84/321 - (26%)
• Similarity: 123/321 - (38%)
• Gaps: 89/321 - (27%)

Human    22 HWCYEVQAESSNYPCLVPVKWG---GNCQKDRQSPINIVTTKAKVDKKLG--------------R 69
            ||.|   .|.:.     |..|.   ......||||::|..:.||...:|.              .
  Fly     4 HWGY---TEENG-----PAHWAKEYPQASGHRQSPVDITPSSAKKGSELNVAPLKWKYVPEHTKS 60

Human    70 FFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGL-PAPYQAKQLHLHWSDLPYKGSEHSLDGE 133
            ....||    .|.|..||..        :.::||.| ...::.:|.|.||.....|||||::||.
  Fly    61 LVNPGY----CWRVDVNGAD--------SELTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGV 113

Human   134 HFAMEMHIVH---EKEKGTSRNVKEAQDPEDEIAVLAFLVEIGRMNWPPPLAPCRLSQDPSL--- 192
            .::.|:|:||   .|.|    :..||....|.:|||...::.|..:       ..|.:..||
  Fly   114 SYSGELHLVHWNTTKYK----SFGEAAAAPDGLAVLGVFLKAGNHH-------AELDKVTSLLQF 167

Human   193 PFQAGTQVN--EGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDE 255
            ....|.:|.  :|..|                      ..|||   .:..|:.|.||||||.|.|
  Fly   168 VLHKGDRVTLPQGCDP----------------------GQLLP---DVHTYWTYEGSLTTPPCSE 207

Human   256 KVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKD-------NVRPLQQLGQRTVIKSG 309
            .|:|.||:.||::..:|:.|......||.::.....:       |.||...||:|.:.:.|
  Fly   208 SVIWIVFKTPIEVSDDQLNAMRNLNAYDVKEECPCNEFNGKVINNFRPPLPLGKRELREIG 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CA4	XP_005257696.1	alpha_CA_IV_XV_like	48..307	CDD:239391	77/288 (27%)
CAH1	NP_523561.1	Carb_anhydrase	5..263	CDD:215000	81/313 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.720