Protein Alignment CA3 and CAH15

DIOPT Version :10

• Sequence 1: NP_005172.1
• Gene: CA3 / 761
• HGNCID: 1374
• Length: 260
• Species: Homo sapiens
• Sequence 2: NP_611525.1
• Gene: CAH15 / 37366
• FlyBaseID: FBgn0034560
• Length: 332
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 62/258 - (24%)
• Similarity: 103/258 - (39%)
• Gaps: 19/258 - (7%)

Human     3 KEWGYASHNGPDHWHELFPNAKGENQSP--VELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKT 65
            :.:.|....||..|     :....||||  ::::..:|.:..:...||..........:.|||.|
  Fly    80 ESYNYDWDQGPHTW-----DTACNNQSPINIDMNCVEINYFDTPLIWSHYNSIPLGIRLENNGHT 139

Human    66 --CRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYN 128
              .|..|.:.  ...:.||.|.|.:..|:....|..:...|||||:|......|:..:|.:   .
  Fly   140 LILRAAFPER--TPSIDGGDLLGRFDFREISFRWSWASSLGSEHTLDHHHSPLEMQCLHTD---G 199

Human   129 TFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLF-PACRDYWT 192
            ...:......|:.:|.....:...|....:.:..|..::..|:......|..|.|. |....:::
  Fly   200 DGCDGCSSSQGVLMISYMFDLSEHNPFLDVLIQHLAAVEQAGQVVEVPPFPLSYLMSPFYDKFYS 264

Human   193 YQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVV 255
            |.||.|.|||.....||:..|.:.:|..|:.:.|.|.....:.    :..|.||.|||.:|:|
  Fly   265 YNGSLTEPPCHRGAEWLIYPESLAISERQLNEFRQLRDRRGSR----IARNARPVQPIGDRMV 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CA3	NP_005172.1	alpha_CA_I_II_III_XIII	1..259	CDD:239393	62/258 (24%)
		Involved in proton transfer. /evidence=ECO:0000269|PubMed:17427958	64..67		1/4 (25%)
CAH15	NP_611525.1	alpha_CARP_receptor_like	82..325	CDD:239396	62/256 (24%)