DRSC/TRiP Functional Genomics Resources

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Protein Alignment MZF1 and CG17806

DIOPT Version :9

Sequence 1:XP_005259261.1 Gene:MZF1 / 7593 HGNCID:13108 Length:775 Species:Homo sapiens
Sequence 2:NP_650658.1 Gene:CG17806 / 42142 FlyBaseID:FBgn0038548 Length:421 Species:Drosophila melanogaster


Alignment Length:292 Identity:77/292 - (26%)
Similarity:113/292 - (38%) Gaps:62/292 - (21%)


- Green bases have known domain annotations that are detailed below.


Human   480 PFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPPAPPGAPEPPGPFPCSECRESFARRAVLLEH 544
            |.||.:..|             :..:|......|.......||....| ...:|......|:.|.
  Fly   151 PLRCEDPIQ-------------VKSEPQLSSDYPVESMNHEEPASEMP-QVMKEEPRTLQVIGEV 201

Human   545 QAVHTGDKSFGCV-EC-------------------GERFGRRSVLLQHRRVHSGE-RPFACAECG 588
            |......:|.||: ||                   .|::..|:.....:|.::.| |.:.|.:||
  Fly   202 QKNRRKPRSKGCLEECPGKDMAKIENIDSTTNKTKEEKYATRNKWGAAKRAYALEHRLYFCDQCG 266

Human   589 QSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLTQHLRV-HTGEKPFACPECGQRFSQRLK 652
            ::|.::.|...|.|.|.|.:.|.|.||.:....:..|..|:|: |.||.|:.|..||:||...||
  Fly   267 KTFSEKGNFNVHLRRHKGTKEFQCQECDRMEFTQHLLNLHVRIKHRGELPYVCKYCGKRFDNCLK 331

Human   653 LTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQHRRIHT 717
            ...|:|.|. |.|.|                        ||..|..|.::|:....|..|..:||
  Fly   332 RLNHERNHK-ESPVH------------------------RPHVCSTCQKAFKTSTALKDHIVVHT 371

Human   718 GERPYACPECGKAFRQRPTLTQHLRT-HRREK 748
            ||:|:.|..|...|.:|..|..|.:: |.|.|
  Fly   372 GEQPFHCELCQTFFNRRNALATHYKSKHHRLK 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MZF1XP_005259261.1 SCAN 81..193 CDD:128708
COG5048 399..757 CDD:227381 77/292 (26%)
C2H2 Zn finger 399..419 CDD:275368
C2H2 Zn finger 427..447 CDD:275368
C2H2 Zn finger 455..475 CDD:275368
C2H2 Zn finger 483..503 CDD:275370 2/19 (11%)
C2H2 Zn finger 528..548 CDD:275368 4/19 (21%)
C2H2 Zn finger 556..576 CDD:275368 6/39 (15%)
C2H2 Zn finger 584..604 CDD:275368 7/19 (37%)
C2H2 Zn finger 612..632 CDD:275368 6/20 (30%)
C2H2 Zn finger 640..660 CDD:275368 9/19 (47%)
C2H2 Zn finger 668..688 CDD:275368 0/19 (0%)
C2H2 Zn finger 696..716 CDD:275368 5/19 (26%)
C2H2 Zn finger 724..744 CDD:275368 6/20 (30%)
C2H2 Zn finger 752..772 CDD:275368
CG17806NP_650658.1 zf-AD 4..76 CDD:285071
zf-C2H2 260..282 CDD:278523 7/21 (33%)
C2H2 Zn finger 262..282 CDD:275368 7/19 (37%)
C2H2 Zn finger 290..311 CDD:275368 6/20 (30%)
COG5048 <298..>383 CDD:227381 34/109 (31%)
C2H2 Zn finger 319..339 CDD:275368 9/19 (47%)
C2H2 Zn finger 350..370 CDD:275368 5/19 (26%)
ZnF_U1 375..407 CDD:197732 10/29 (34%)
C2H2 Zn finger 378..396 CDD:275368 6/17 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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