Protein Alignment ZNF41 and CG5245

DIOPT Version :10

• Sequence 1: NP_001311084.1
• Gene: ZNF41 / 7592
• HGNCID: 13107
• Length: 821
• Species: Homo sapiens
• Sequence 2: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 178/470 - (37%)
• Similarity: 255/470 - (54%)
• Gaps: 41/470 - (8%)

Human   339 KSREC-DKSNKVFPQKPQVDVHPSVYTGEKPYLCTQCGKVFTLKSNLITHQKIHTGQKPYKCSEC 402
            |.:.| .|..|..|.:.|.|.          :.||||.|.||.|.||.:|.::|..::|::||.|
  Fly    61 KLKTCKSKIAKKRPLRKQTDT----------FKCTQCQKTFTRKENLESHLRLHAEERPFECSHC 115

Human   403 GKAFFQRSDLFRHLRIHTGEKPYECSECGKGFSQNSDLSIHQKTHTGEKHYECNECGKAFTRKSA 467
            .|:|.:|:...|||..|. ::|::||.|.|.|:|||.|..|...||||:.::|.:|..:|.|||.
  Fly   116 SKSFGRRTHYKRHLLKHE-KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSH 179

Human   468 LRMHQRIHTGEKPYVCADCGKAFIQKSHFNTHQRIHTGEKPYECSDCGKSFTKKSQLHVHQRIHT 532
            |::|.|.|:.|:|:.|..|.|||...||...|.|.|...:|::||.|.|||..:|.|..|
  Fly   180 LQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKH----- 239

Human   533 GEKPYICTECGKVFTHRTNLTTHQKTHTGEKPYMCAECGKAFTDQSNLIKHQKTHTGEKPYKCNG 597
                               |.||     .|:.:.|.:|.|.|....:|..|.:.|.||.|:||..
  Fly   240 -------------------LLTH-----AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPH 280

Human   598 CGKAFIWKSRLKIHQKSHIGERHYECKDCGKAFIQKSTLSVHQRIHTGEKPYVCPECGKAFIQKS 662
            |.:.|...|||::|...|.|:...:|..|...|..:|...||.|:||.|:.|.|.||.|:|.:||
  Fly   281 CSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKS 345

Human   663 HFIAHHRIHTGEKPYECSDCGKCFTKKSQLRVHQKIHTGEKPNICAECGKAFTDRSNLITHQKIH 727
            |.:.|.::||||:|::|:.|.|.|..::.||||...|.|||...|:.|.|.|...|.|:.|.:.|
  Fly   346 HLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEH 410

Human   728 TREKPYECGDCGKTFTWKSRLNIHQKSHTGERHYECSKCGKAFIQKATLSMHQIIHTGKKPYACT 792
            |.:..:||..|.|::|..|.|::|.::||||..::||.|.|.|.:.|....|...|||:|||.|:
  Fly   411 TGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCS 475

Human   793 ECQKAFTDRSNLIKH 807
            .|...:|.:|:|.:|
  Fly   476 HCSTRYTQKSSLGRH 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF41	NP_001311084.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		KRAB	69..129	CDD:214630
		C2H2 Zn finger	315..335	CDD:275368
		COG5048	346..768	CDD:227381	159/421 (38%)
		C2H2 Zn finger	371..391	CDD:275368	11/19 (58%)
		C2H2 Zn finger	399..419	CDD:275368	9/19 (47%)
		C2H2 Zn finger	427..447	CDD:275368	10/19 (53%)
		C2H2 Zn finger	455..475	CDD:275368	9/19 (47%)
		C2H2 Zn finger	483..503	CDD:275368	9/19 (47%)
		C2H2 Zn finger	511..531	CDD:275368	9/19 (47%)
		C2H2 Zn finger	539..559	CDD:275368	3/19 (16%)
		C2H2 Zn finger	567..587	CDD:275368	6/19 (32%)
		C2H2 Zn finger	595..615	CDD:275368	7/19 (37%)
		C2H2 Zn finger	623..643	CDD:275368	7/19 (37%)
		C2H2 Zn finger	651..671	CDD:275368	9/19 (47%)
		C2H2 Zn finger	679..699	CDD:275368	8/19 (42%)
		C2H2 Zn finger	707..727	CDD:275368	7/19 (37%)
		C2H2 Zn finger	735..755	CDD:275368	7/19 (37%)
		C2H2 Zn finger	763..783	CDD:275368	7/19 (37%)
		C2H2 Zn finger	791..811	CDD:275368	6/17 (35%)
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	169/443 (38%)
		C2H2 Zn finger	84..104	CDD:275368	11/19 (58%)
		C2H2 Zn finger	112..132	CDD:275368	9/19 (47%)
		C2H2 Zn finger	139..159	CDD:275368	10/19 (53%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	9/19 (47%)
		C2H2 Zn finger	223..243	CDD:275368	10/43 (23%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	9/19 (47%)
		C2H2 Zn finger	362..382	CDD:275368	8/19 (42%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)