DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZNF41 and crol

DIOPT Version :10

Sequence 1:NP_001311084.1 Gene:ZNF41 / 7592 HGNCID:13107 Length:821 Species:Homo sapiens
Sequence 2:NP_477243.1 Gene:crol / 34592 FlyBaseID:FBgn0020309 Length:962 Species:Drosophila melanogaster


Alignment Length:556 Identity:214/556 - (38%)
Similarity:292/556 - (52%) Gaps:38/556 - (6%)


- Green bases have known domain annotations that are detailed below.


Human   261 GNGNNFPHSPSSTKNENAKTGANSCEHDHYEKHLSHKQAPTHHQKIHPEEKLYVCTECVMGFTQK 325
            |.|.|...:|..|.   ..||.:.|  |...|....:.....|::.|.|.|.::|..|..|||..
  Fly   202 GGGQNVALAPDGTP---IATGTHVC--DICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTS 261

Human   326 SHLFEHQRIHAGEKSRECDKSNKVFPQKPQVDVHPSVYTGEKPYLCTQCGKVFTLKSNLITHQKI 390
            ..|..|.:||.|.....|.....||.....::.|...::.:||:.||.|.|.|..|.:|..|.:.
  Fly   262 QDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRS 326

Human   391 HTGQKPYKCSECGKAFFQRSDLFRHLRIHTGEKPYECSECGKGFSQNSDLSIHQKTHTGEKHYEC 455
            |||:.|::|..|.|.|.::..:..|:|.||||.|:.|..|.|.|::......|...|||:..::|
  Fly   327 HTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQC 391

Human   456 NECGKAFTRKSALRMHQRIHTGEKPYVCADCGKAFIQKSHFNTHQRIHTGEKPYECSDCGKSFTK 520
            :.|||.:|||..|..|.|.||.|.|:.|..|||:|.:|.||..|...||||.|:.|..|.|:||:
  Fly   392 DVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTR 456

Human   521 KSQLHVHQRIHTGEKPYICTECGKVFTHRTNLTTHQKTHTGEKPYMCAECGKAFTDQSNLIKHQK 585
            |..|..|.|.||||.|:.|:.|.|.||.:.:|..|.:.||||.|:.|..|.||||.:.:::.|.:
  Fly   457 KEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVR 521

Human   586 THTGEKPYKCNGCGKAFIWKSRLKIHQKSHIGERHYECKDCGKAFIQKSTLSVHQRIHTGEKPYV 650
            .||||.|:||.                        |    |.|.|.:|..|:.|.|.|||:.|:.
  Fly   522 QHTGESPHKCT------------------------Y----CTKTFTRKEHLTNHVRQHTGDSPHR 558

Human   651 CPECGKAFIQKSHFIAHHRIHTGEKPYECSDCGKCFTKKSQLRVHQKIHTGEKPNICAECGKAFT 715
            |..|.|.|.:|.|...|.|:|||:.|::|..|.|.||:|..|..|.:.|:.:.|:.|..|.|.||
  Fly   559 CSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFT 623

Human   716 DRSNLITH-QKIHTREKPYECGDCGKTFTWKSRLNIHQKSHTG----ERHYECSKCGKAFIQKAT 775
            .:.:||.| .:.||.::|:.|..|||:|..|..|..||:|||.    ||.:.|.||.|.||.|..
  Fly   624 RKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGH 688

Human   776 LSMHQIIHTGKKPYACTECQKAFTDRSNLIKHQKMH 811
            |..|...|:|:||:|||.|.|||.:|.||.:|.||:
  Fly   689 LVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMN 724

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZNF41NP_001311084.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..55
KRAB 69..129 CDD:214630
C2H2 Zn finger 315..335 CDD:275368 7/19 (37%)
COG5048 346..768 CDD:227381 166/426 (39%)
C2H2 Zn finger 371..391 CDD:275368 8/19 (42%)
C2H2 Zn finger 399..419 CDD:275368 6/19 (32%)
C2H2 Zn finger 427..447 CDD:275368 5/19 (26%)
C2H2 Zn finger 455..475 CDD:275368 10/19 (53%)
C2H2 Zn finger 483..503 CDD:275368 9/19 (47%)
C2H2 Zn finger 511..531 CDD:275368 9/19 (47%)
C2H2 Zn finger 539..559 CDD:275368 7/19 (37%)
C2H2 Zn finger 567..587 CDD:275368 7/19 (37%)
C2H2 Zn finger 595..615 CDD:275368 1/19 (5%)
C2H2 Zn finger 623..643 CDD:275368 7/19 (37%)
C2H2 Zn finger 651..671 CDD:275368 8/19 (42%)
C2H2 Zn finger 679..699 CDD:275368 8/19 (42%)
C2H2 Zn finger 707..727 CDD:275368 8/20 (40%)
C2H2 Zn finger 735..755 CDD:275368 9/19 (47%)
C2H2 Zn finger 763..783 CDD:275368 9/19 (47%)
C2H2 Zn finger 791..811 CDD:275368 11/19 (58%)
crolNP_477243.1 C2H2 Zn finger 223..243 CDD:275368 4/21 (19%)
C2H2 Zn finger 251..271 CDD:275368 7/19 (37%)
C2H2 Zn finger 279..299 CDD:275368 4/19 (21%)
COG5048 300..723 CDD:227381 184/450 (41%)
C2H2 Zn finger 307..327 CDD:275368 8/19 (42%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
C2H2 Zn finger 363..383 CDD:275368 5/19 (26%)
C2H2 Zn finger 391..411 CDD:275368 10/19 (53%)
C2H2 Zn finger 419..439 CDD:275368 9/19 (47%)
C2H2 Zn finger 447..467 CDD:275368 9/19 (47%)
C2H2 Zn finger 475..495 CDD:275368 7/19 (37%)
C2H2 Zn finger 503..523 CDD:275368 7/19 (37%)
C2H2 Zn finger 531..551 CDD:275368 9/47 (19%)
C2H2 Zn finger 559..579 CDD:275368 8/19 (42%)
C2H2 Zn finger 587..607 CDD:275368 8/19 (42%)
C2H2 Zn finger 615..636 CDD:275368 8/20 (40%)
C2H2 Zn finger 644..664 CDD:275368 9/19 (47%)
C2H2 Zn finger 676..696 CDD:275368 9/19 (47%)
C2H2 Zn finger 704..722 CDD:275368 10/17 (59%)
Blue background indicates that the domain is not in the aligned region.

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