DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZNF32 and CG17612

DIOPT Version :9

Sequence 1:	NP_001311093.1	Gene:	ZNF32 / 7580	HGNCID:	13095	Length:	277	Species:	Homo sapiens
Sequence 2:	NP_608824.1	Gene:	CG17612 / 33639	FlyBaseID:	FBgn0031597	Length:	618	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	72/277 - (25%)
Similarity:	121/277 - (43%)	Gaps:	38/277 - (13%)

- Green bases have known domain annotations that are detailed below.

Human    23 RRPCFDVMTEAHHKYDHSEATGSSSWD--------IQNSFRREKLEQKSPDSKTLQEDSPGVRQR 79
            :|.|.:.....|...|..|:.....:.        :.:||....::.....|:.|.      |:.
  Fly   332 KRGCLEAHMWIHRASDERESELEPPYRCPHCPKLFLYSSFLEIHIQTHEDVSQRLS------RKS 390

Human    80 VYECQECGKSFRQKGSLTLHERIHTGQKPFECTHCGKSFRAKGNLVTHQRIHTGEKPYQCKECGK 144
            .::|.:|...|....||..|.:||.|::.|:|..|..||:.:.||.:|...||   .::|.:|.|
  Fly   391 SHKCAQCADVFSDVSSLKDHVKIHAGERTFKCPLCLMSFQEESNLKSHDCAHT---RFKCHKCSK 452

Human   145 SFSQRGSLAVH-ERLHTGQKPYECAICQRSFRNQSNLAVH---------RRVHSGEKPYRCDQCG 199
            .|..:..|..| ::.||.:.|::|..||::|:.::.|..|         .|..|..:.:.|.:|.
  Fly   453 FFESQNYLDFHFKKSHTTKGPFKCIKCQQTFQKRNGLKEHISSQVCVQFLRSKSPGQIFPCPKCP 517

Human   200 KAFSQKGSLIVHIRVH----TGLKPYACTQCRKSFHTRGNCILHGKIHTGETPYLCGQCGKSFTQ 260
            |.||.:.:..:|...|    |.::.:.||||:||:..:.....|...|.     .|..|..|||.
  Fly   518 KKFSIEDNYQMHHATHKKVKTVIERHNCTQCKKSYQNKKLLTKHILSHN-----RCVHCSMSFTS 577

Human   261 RGSLAVHQRSCSQRLTL 277
            :  ..:.|.:|||...|
  Fly   578 K--YLLEQHTCSQSYQL 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZNF32	NP_001311093.1	COG5048	<51..241	CDD:227381	56/203 (28%)
		C2H2 Zn finger	83..103	CDD:275368	6/19 (32%)
		C2H2 Zn finger	111..131	CDD:275368	7/19 (37%)
		C2H2 Zn finger	139..159	CDD:275368	6/20 (30%)
		C2H2 Zn finger	167..187	CDD:275368	7/28 (25%)
		C2H2 Zn finger	195..215	CDD:275368	6/19 (32%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	251..269	CDD:275368	5/17 (29%)
CG17612	NP_608824.1	zf-AD	187..>246	CDD:285071
		C2H2 Zn finger	290..310	CDD:275368
		C2H2 Zn finger	323..343	CDD:275370	2/10 (20%)
		zf-C2H2_8	356..438	CDD:292531	21/87 (24%)
		C2H2 Zn finger	359..379	CDD:275368	2/19 (11%)
		C2H2 Zn finger	394..414	CDD:275368	6/19 (32%)
		C2H2 Zn finger	422..438	CDD:275368	6/15 (40%)
		C2H2 Zn finger	447..463	CDD:275368	5/15 (33%)
		C2H2 Zn finger	476..505	CDD:275368	7/28 (25%)
		C2H2 Zn finger	513..533	CDD:275368	6/19 (32%)
		C2H2 Zn finger	545..565	CDD:275368	7/19 (37%)
		C2H2 Zn finger	568..584	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000