Protein Alignment Brsk2 and par-1

DIOPT Version :9

• Sequence 1: NP_001009930.1
• Gene: Brsk2 / 75770
• MGIID: 1923020
• Length: 719
• Species: Mus musculus
• Sequence 2: NP_995894.2
• Gene: par-1 / 2768852
• FlyBaseID: FBgn0260934
• Length: 1170
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 196/607 - (32%)
• Similarity: 296/607 - (48%)
• Gaps: 89/607 - (14%)

Mouse    15 QYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHV 79
            :::|.|:|.||:|||....|||..|..|.::|||||:::.:|:...|.|:.||:.|:|:::||::
  Fly   248 EHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNI 312

Mouse    80 LKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLK 144
            :||..|.|.:|.|||::|:.||||:|||||..||:..||||..||||:||:.:||...|.|||||
  Fly   313 VKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLK 377

Mouse   145 PENLLLDERNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFA 209
            .||||||...||:|||||.::.....|.|:|.||||.||.||:.:|:||||.:.||||.||||:.
  Fly   378 AENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYT 442

Mouse   210 LLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGG 274
            |:.|:||||...||:|.|:|.||.:.:|.::..||::|||..:.::.|:|.:||.|....|...|
  Fly   443 LVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMG 507

Mouse   275 KNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLL 339
            ..|.|.:..|..|..:        .||..::::.::|..|..   ::..||:....:....:|||
  Fly   508 FEEDELKPYIEPKADL--------ADPKRIEALVAMGYNRSE---IEASLSQVRYDDVFATYLLL 561

Mouse   340 DRKERYPSHEDEDLPPRNEIDPPRKRVDSPMLNRHGKRRPERKSMEVLSVTDGGSPVPARRAIEM 404
            .||...|..:                         |.|.....|:..:|..|.|:.. ...:::.
  Fly   562 GRKSTDPESD-------------------------GSRSGSSLSLRNISGNDAGANA-GSASVQS 600

Mouse   405 AQHGQRSRSISG--------ASSGL-----------------STSPLSSPRVTPHPSPR---GSP 441
            ..|....||||.        ||||:                 :.:|.::.......:.|   ||.
  Fly   601 PTHRGVHRSISASSTKPSRRASSGVGPTNAAATVAAATGAVGAVNPSNNYNAAGSAADRASVGSN 665

Mouse   442 LPTPKGTPVHTPKESPA--GTPNPTPPSSPSVGGVPWRTRLNSIKNSFLGSPRFHRRKLQVP--- 501
            ..........|.||:.|  ...|..|.|:..        ::.:..::.|.||...|...:..
  Fly   666 FKRQNTIDSATIKENTARLAAQNQRPASATQ--------KMLTTADTTLNSPAKPRTATKYDPTN 722

Mouse   502 ---TPEEMSNLTPESSPELAKKSWFGNFIN-LEKEEQIFVVIKDKPLSSIKADIVHAFLSIPSLS 562
               |....|.:.|..|..|.:|:......| :..|..:|..:  :..|::|:. .|...::||.|
  Fly   723 GNRTVSGTSGIIPRRSTTLYEKTSSTEKTNVIPAETNLFDRL--RMASAVKSS-RHFPRNVPSRS 784

Mouse   563 HSVISQTSFR----AEYKATGG 580
            .....||..|    .||..|.|
  Fly   785 TFHSGQTRARNNTALEYSGTSG 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brsk2	NP_001009930.1	STKc_BRSK1_2	18..271	CDD:270983	126/252 (50%)
		UBA_BRSK	298..351	CDD:270525	12/52 (23%)
par-1	NP_995894.2	STKc_MARK	252..504	CDD:270974	125/251 (50%)
		S_TKc	253..504	CDD:214567	125/250 (50%)
		UBA_MARK_Par1	525..563	CDD:270522	9/40 (23%)
		MARK1-3_C	839..936	CDD:213381

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D302185at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920