DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ZNF708 and ranshi

DIOPT Version :9

Sequence 1:	XP_016882693.1	Gene:	ZNF708 / 7562	HGNCID:	12945	Length:	587	Species:	Homo sapiens
Sequence 2:	NP_649824.1	Gene:	ranshi / 41041	FlyBaseID:	FBgn0037620	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	96/368 - (26%)
Similarity:	139/368 - (37%)	Gaps:	78/368 - (21%)

- Green bases have known domain annotations that are detailed below.

Human   132 VTTTQSKIVQCDKYVKVFHKYSNAKRHKIR-HTGKNPFKCKECGKSFCMLSQL------------ 183
            |..|..|....::.:.:|.|.:......|: .||.....|.......|...|.
  Fly     5 VCRTCGKRTNAERSLNIFEKRNQTTLEHIKLLTGAVLKNCSTLPNRLCASCQTCLQQAISFRERC 69

Human   184 --TQHEIIHTGEKP---YKCEECGKAFKKSSNL---------TNHKIIHTGEKPYKCEECGKAFN 234
              .|.|::|:.:..   ..|:|..|:..:...|         ...::....|.|.:    ...|.
  Fly    70 LEVQRELLHSQDDEDFLRICQESPKSVLEQEELELDLAEISIEVERLDDLNEGPIQ----SSGFK 130

Human   235 QSSTLTRHKI----------IHTGEKLYKCEECGKAFNRSSNLTKHKIVHTGEKPYK-------- 281
            ....|...||          |...|..|...|.....:     .|.::....|.|.|
  Fly   131 VEDILNESKINEDEPNNEDDIDYSEMDYLIYESDTEVD-----AKQELKSDSENPKKRRNRRNPR 190

Human   282 -------CEECGKAFKQSSNLTNHKKIHTGEKPYKCGECGKAFTLSSHLTTHKRIHTGEKPYKCE 339
                   |||||...|...:...|.|.|.|.|.:.|..|...|...:.|..|.|.||||||:||.
  Fly   191 DSNRTFFCEECGNHIKDRISFILHCKRHRGVKEFGCEFCEDRFCTPAELKRHIRKHTGEKPFKCR 255

Human   340 ECGKAFSVFSTLTKHKIIHTEEKPYKCEECGKAFNRSSHLTNHKVIHTGEKPYKCEECGKAFTKS 404
            .|.::||.:||..||:..||.|:|:.|:||..||..|..|.||.::|||||.::|:.|.|.|::.
  Fly   256 HCSRSFSDYSTRLKHERTHTNERPFVCKECNNAFTTSYILKNHMLVHTGEKAFRCDLCDKLFSRY 320

Human   405 STLTYHKVIHTGKKPYKCEECGKAFSIFSILTKHKVIHTEDKP 447
            :.||.|...:..::..:     ||.:||            |||
  Fly   321 THLTTHYRSNAHRRNMQ-----KADTIF------------DKP 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZNF708	XP_016882693.1	None
ranshi	NP_649824.1	zf-AD	5..77	CDD:214871	13/71 (18%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		COG5048	222..>276	CDD:227381	23/53 (43%)
		C2H2 Zn finger	226..246	CDD:275368	6/19 (32%)
		zf-H2C2_2	238..262	CDD:290200	12/23 (52%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		zf-H2C2_2	269..291	CDD:290200	11/21 (52%)
		C2H2 Zn finger	282..302	CDD:275368	9/19 (47%)
		zf-H2C2_2	295..319	CDD:290200	12/23 (52%)
		C2H2 Zn finger	310..328	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000