DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZNF711 and CG8944

DIOPT Version :9

Sequence 1:XP_011529321.1 Gene:ZNF711 / 7552 HGNCID:13128 Length:811 Species:Homo sapiens
Sequence 2:NP_573065.1 Gene:CG8944 / 32517 FlyBaseID:FBgn0030680 Length:762 Species:Drosophila melanogaster


Alignment Length:815 Identity:149/815 - (18%)
Similarity:274/815 - (33%) Gaps:244/815 - (29%)


- Green bases have known domain annotations that are detailed below.


Human   115 HILTSELITETV-----RVPEQVFVADLVTGPNGHLE--HVVQDCVSGVDSPTMVSEEVLVTNSD 172
            |:.|..|..::|     |:|..:.....::|.||.|.  |.::|.   .|:.|.:.|..:|...:
  Fly    54 HMQTVHLGDQSVANTSSRLPFNLGEPMSLSGRNGDLPNFHEIEDL---TDADTALLEPQMVIKQE 115

Human   173 TETVIQAAGGVPGSTVTIKTEDDDDDDVK----STSEDYLMISLDD-------------VGEKLE 220
            .:       .:|.|...:...::|||:.:    ...||..::...|             |.::.:
  Fly   116 LQ-------DLPCSDDDVVAGEEDDDEQRLNDSEADEDEAILPESDVPVVSSKTRARKKVTKQRQ 173

Human   221 HMGNTPLKIGSDGSQEDAKEDGFGSEVIKVYIFKAEAE-------DDVEIGGTEIVTESEYTSGH 278
            ...::.|.|..||   |:..|.:| :....|:.....|       |.|...|  ..|||::.|..
  Fly   174 RDMSSELLIAGDG---DSSMDDYG-DPDHSYMDDNSGEYMDFAGFDGVNHSG--FGTESDFLSYD 232

Human   279 SVAGVLDQSRMQREKMVYMAVKD---------------------SSQEEDDISCAEIADEVYMEV 322
            .   ::::|.:.|::.|.|.:||                     ::|..|.:..|...|.:.:|.
  Fly   233 E---MVEESLLGRDREVTMHIKDRKMIQFLIHSYQRNPFLWDHGNAQFRDRVKRARFLDWIVLEF 294

Human   323 IVGEEEGTSLPEIQLEDSDVNKTVVPVVWAAAYGDERRVSRRYEDCQASGNTLDSALESRSSTAA 387
                            .|..|.::........:.:.|.|.:|  :|..      .|||..:.:..
  Fly   295 ----------------KSRFNISLAKDAITRKWDNLRTVYKR--ECNR------MALEKTNISTL 335

Human   388 QYLQICDGIN---------TNKVLKQKAKKRRRGETRQWQTAVIIGPDGQPLTVYPCHICTKKFK 443
            .|.:....:|         ::.|:|:.:.:||....  |...                 .|.|..
  Fly   336 WYFKELHFLNEVYSYNDKMSDAVVKETSYRRRFSAI--WNDT-----------------STAKLL 381

Human   444 SRGFLKRHMKNHPDHLMRKKYQC----TDCDFTTNKKVSFHNHLESHKLINKVDKTH-------- 496
            |               |.|:|||    .|.|:.:.::.....|..:.:|...:|.|.        
  Fly   382 S---------------MVKRYQCFYNRFDPDYRSKERRGEGLHQMAIELQQLIDVTTIQISKRIS 431

Human   497 --EFTEYTRRYRE------------ASPLSSNKLILRDKEPKMHKCKYCDYETAEQGLLNRHLLA 547
              .| :|:::..|            |:.|..:::...|.:....||.:|.........|:.|:| 
  Fly   432 QLRF-DYSKQKMERLNSERLGKKFIANYLYYDQMHFMDDDIPPFKCAHCPEIVQTLRELDLHML- 494

Human   548 VHSKNF--PHVCVECGKGFRHPSELKKHMRTHTG---EKPYQCQYCIFRCADQSNLKTHIKSKHG 607
            .|..:.  .:.|..|...|.:..|...|.:.|.|   |..:.|:.|.....:::|...|:: :|.
  Fly   495 THQPSLGGGYYCNICSIQFHNAQEFDNHKQLHLGGVTEIKFNCELCTASFREKANYDEHLR-RHN 558

Human   608 NNL---PYKCEHCPQAFG---DERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKD 666
            ..|   .....|.....|   ||..::..               :.:.:.|...:||.... |.|
  Fly   559 EELFLPSLALNHSIMEGGLGDDEIGVEGE---------------ESRGSGSRRKRRHAAKA-TDD 607

Human   667 F------------------------PHKCEVCDKGFHRPSELKKHSDIHKGRKIHQCRHCDFKTS 707
            .                        |:.|:||.:.|..|..|..|..:|:..: .:|..||:   
  Fly   608 MVDDDDRIGGGGGGGSGGGGTDIAKPYGCDVCRRSFATPGHLNAHRIVHQDER-ERCYKCDY--- 668

Human   708 DPFILSGHILSVHTKDQPLKCKRCKRGFRQQNELKKHMKTHTGRKIYQCEYCEYSTTDASGFKRH 772
                                 .:|.:.|..:|.|.:|:|.|...:.::|:.|..:.......:.|
  Fly   669 ---------------------PQCNKSFVARNSLFEHLKQHYSNEEFKCDICGKTFKSTKNLQNH 712

Human   773 VISIHTKDYPHRCEFCKKGFRRPSEKNQHIMRHHK 807
            . .||.|...:.|:.|...|.:.:....|..||::
  Fly   713 K-QIHDKIKRYVCQICGSAFAQAAGLYLHKRRHNR 746

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZNF711XP_011529321.1 Zfx_Zfy_act 69..418 CDD:282547 67/363 (18%)
COG5048 <426..604 CDD:227381 39/208 (19%)
zf-C2H2 433..455 CDD:278523 3/21 (14%)
C2H2 Zn finger 435..455 CDD:275368 3/19 (16%)
C2H2 Zn finger 528..549 CDD:275368 5/20 (25%)
COG5048 550..>807 CDD:227381 54/291 (19%)
zf-C2H2 555..577 CDD:278523 5/21 (24%)
C2H2 Zn finger 557..577 CDD:275368 5/19 (26%)
zf-H2C2_2 569..593 CDD:290200 7/26 (27%)
C2H2 Zn finger 585..606 CDD:275368 4/20 (20%)
C2H2 Zn finger 614..640 CDD:275368 4/28 (14%)
C2H2 Zn finger 642..663 CDD:275368 3/20 (15%)
C2H2 Zn finger 671..720 CDD:275368 11/48 (23%)
C2H2 Zn finger 728..748 CDD:275368 6/19 (32%)
zf-H2C2_2 740..764 CDD:290200 6/23 (26%)
C2H2 Zn finger 756..777 CDD:275368 3/20 (15%)
C2H2 Zn finger 785..805 CDD:275368 4/19 (21%)
CG8944NP_573065.1 MADF_DNA_bdg 259..344 CDD:287510 15/108 (14%)
MADF 379..472 CDD:214738 19/108 (18%)
C2H2 Zn finger 476..496 CDD:275368 5/20 (25%)
C2H2 Zn finger 506..526 CDD:275368 5/19 (26%)
C2H2 Zn finger 537..557 CDD:275368 4/20 (20%)
C2H2 Zn finger 636..656 CDD:275368 7/19 (37%)
zf-C2H2_8 639..712 CDD:292531 18/97 (19%)
C2H2 Zn finger 666..688 CDD:275368 8/45 (18%)
zf-C2H2 694..716 CDD:278523 3/22 (14%)
C2H2 Zn finger 696..716 CDD:275368 3/20 (15%)
zf-H2C2_2 708..733 CDD:290200 7/25 (28%)
C2H2 Zn finger 724..744 CDD:275368 4/19 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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