DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZFX and CG8089

DIOPT Version :9

Sequence 1:NP_001317256.1 Gene:ZFX / 7543 HGNCID:12869 Length:844 Species:Homo sapiens
Sequence 2:NP_611014.1 Gene:CG8089 / 36679 FlyBaseID:FBgn0033993 Length:624 Species:Drosophila melanogaster


Alignment Length:392 Identity:83/392 - (21%)
Similarity:136/392 - (34%) Gaps:79/392 - (20%)


- Green bases have known domain annotations that are detailed below.


Human   497 CTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCK 561
            |..|:....||:   ..:|.|:.|.:......|..|.:.|....:|.:| ::.|...:.::|:.|
  Fly   171 CYKCENLPWKKL---QDVEDHQKTHRYSDNFHCQICYRRFYLQHSLTSH-IIRKSTSSRELHENK 231

Human   562 FCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGF--------RHPSELKKHMRIHTGEKPYQCQ 618
            ..:.....|.......|.:.......|.|...:..        :||.:.:|...:.      :|.
  Fly   232 RYKRLLENQKSQEEKELELSLNKVEDILVPVAEDLQSYFKDESKHPIQKRKTSSLS------KCP 290

Human   619 YCEYRSADSSNLKTHVKTKHSKE-----MPFKCDICLLTFSDTKEVQQH--------ALIHQESK 670
            .|......|.:.:.|: .||.:|     .||.|..|..:|...|.:::|        .|:::..|
  Fly   291 SCAQNYGFSFSHQLHM-VKHRRERLYTNFPFHCSFCNRSFLTRKFLRKHQQRVRTFSTLLYRPFK 354

Human   671 THQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDK-------GFHRPSELKKHVAAHKGK-- 726
               |.||..:....|.|..|::.:|.:..|  |.:|..       ..|...|..:.:..::.|  
  Fly   355 ---CPHCTWRFQLKSALDSHVLRIHERRKP--CLICKLPTSRLCCSAHTSKECNRAMQKYRDKMR 414

Human   727 -------------KMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMK 778
                         ....|:.|:.|....|.|..|:...|.....|.|:.|...|..|..::.|.|
  Fly   415 PLREPPKGGCRKQPTPVCKICNRKFTRKFFLEEHMNKAHLNKRNFTCEICGANFYSQGTMQTHRK 479

Human   779 -THSGRKVYQCEYCEYSTTDASGFKRHVIS-IH-------------TKDYPHRCEYCKKGFRRPS 828
             .|......|||.|:.:......::||..| .|             |||...|     ||.|...
  Fly   480 AVHLLVHTVQCEVCDLTIKSKGNYRRHCKSQSHKDNLVKFGKNNDKTKDSNRR-----KGARTTD 539

Human   829 EK 830
            ||
  Fly   540 EK 541

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZFXNP_001317256.1 None
CG8089NP_611014.1 C2H2 Zn finger 289..309 CDD:275368 4/20 (20%)
C2H2 Zn finger 322..343 CDD:275368 5/20 (25%)
C2H2 Zn finger 355..376 CDD:275368 6/20 (30%)
C2H2 Zn finger 432..453 CDD:275368 6/20 (30%)
C2H2 Zn finger 461..486 CDD:275368 7/24 (29%)
C2H2 Zn finger 490..506 CDD:275368 3/15 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24406
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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