Protein Alignment ZFX and rst2

DIOPT Version :10

• Sequence 1: NP_001317256.1
• Gene: ZFX / 7543
• HGNCID: 12869
• Length: 844
• Species: Homo sapiens
• Sequence 2: NP_593288.1
• Gene: rst2 / 2543031
• PomBaseID: SPAC6F12.02
• Length: 567
• Species: Schizosaccharomyces pombe
• Alignment Length: 129
• Identity: 33/129 - (25%)
• Similarity: 52/129 - (40%)
• Gaps: 23/129 - (17%)

Human   652 TFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYP---------HKCDMCD 707
            |.|::|..:....|:.:|.|.   :.:..||.:|:.|....|...|..|         :.|:.|.
pombe    15 TLSESKVSENLMSINSDSGTS---NANTPSSVTSNSKPVASSTAAKKDPNAPPQKVKQYVCETCT 76

Human   708 KGFHRPSELKKHVAAHKGKKMHQCRHCD---------FKIADPFVLSRHILSVHTKDLPFRCKR 762
            :.|.|...||:|:.:|..:|...|...|         |...|  :|.||...:|....|.|.:|
pombe    77 RAFARLEHLKRHIRSHTNEKPFTCSEIDGLPTGCGRQFSRRD--LLLRHQQKIHRNPQPRRRRR 138

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZFX	NP_001317256.1	Zfx_Zfy_act	109..449	CDD:461400
		ROS_MUCR	<416..>496	CDD:473244
		C2H2 Zn finger	466..486	CDD:275368
		C2H2 Zn finger	497..521	CDD:275368
		C2H2 Zn finger	529..549	CDD:275368
		COG5048	582..>719	CDD:227381	19/75 (25%)
		C2H2 Zn finger	589..609	CDD:275368
		C2H2 Zn finger	617..636	CDD:275368
		C2H2 Zn finger	674..695	CDD:275368	5/20 (25%)
		C2H2 Zn finger	703..723	CDD:275368	7/19 (37%)
		zf-C2H2	758..780	CDD:395048	2/5 (40%)
		C2H2 Zn finger	760..780	CDD:275368	1/3 (33%)
		zf-H2C2_2	772..796	CDD:463886
		C2H2 Zn finger	788..809	CDD:275368
		C2H2 Zn finger	817..837	CDD:275368
rst2	NP_593288.1	COG5048	37..547	CDD:227381	27/104 (26%)
		C2H2 Zn finger	72..92	CDD:275368	7/19 (37%)
		C2H2 Zn finger	100..128	CDD:275368	7/29 (24%)