Protein Alignment YWHAZ and 14-3-3epsilon

DIOPT Version :9

• Sequence 1: NP_001129171.1
• Gene: YWHAZ / 7534
• HGNCID: 12855
• Length: 245
• Species: Homo sapiens
• Sequence 2: NP_732309.1
• Gene: 14-3-3epsilon / 42186
• FlyBaseID: FBgn0020238
• Length: 262
• Species: Drosophila melanogaster
• Alignment Length: 245
• Identity: 164/245 - (66%)
• Similarity: 197/245 - (80%)
• Gaps: 4/245 - (1%)

Human     2 DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIE 66
            ::...|.||||||||||||:|...||.|.....||:.|||||||||||||:||||:|||:::|||
  Fly     3 ERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITSIE 67

Human    67 QKTE--GAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYL 129
            ||.|  |||:|.:|.:.||.::|.||||||:|:|::|||.|||.|:..||||||.||||||:|||
  Fly    68 QKEENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHRYL 132

Human   130 AEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKT 194
            ||.|.|.|:|...:.|..||:.|.:|:..::.||||||||||||||||||||||||::||.|||.
  Fly   133 AEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKA 197

Human   195 AFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAE--AGEG 242
            |||:|||||||||||||||||||||||||||||||||.|.:|.:  ||:|
  Fly   198 AFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAGDG 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YWHAZ	NP_001129171.1	14-3-3_beta_zeta	2..230	CDD:206758	156/229 (68%)
14-3-3epsilon	NP_732309.1	14-3-3_epsilon	4..233	CDD:206757	156/228 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100283
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1059
SonicParanoid	1	1.000	-	-		X206
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.860