Protein Alignment YWHAZ and par-5

DIOPT Version :10

• Sequence 1: NP_003397.1
• Gene: YWHAZ / 7534
• HGNCID: 12855
• Length: 245
• Species: Homo sapiens
• Sequence 2: NP_001369936.1
• Gene: par-5 / 178113
• WormBaseID: WBGene00003920
• Length: 248
• Species: Caenorhabditis elegans
• Alignment Length: 240
• Identity: 189/240 - (78%)
• Similarity: 213/240 - (88%)
• Gaps: 2/240 - (0%)

Human     5 ELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKT 69
            ||||:|||||||||||||||.||.|||||.|||||||||||||||||||||||||||:|||||||
 Worm     7 ELVQRAKLAEQAERYDDMAAAMKKVTEQGQELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKT 71

Human    70 EGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAA 134
            ||:|||||:|:|||.|:|.||.|||.|||.||::|||..|..||||||||||||||||||||||:
 Worm    72 EGSEKKQQLAKEYRVKVEQELNDICQDVLKLLDEFLIVKAGAAESKVFYLKMKGDYYRYLAEVAS 136

Human   135 GDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEA 199
             :|:..:|::||:|||||.:|:|.:||||||||||||||||||||||||:||.||.|||.|||:|
 Worm   137 -EDRAAVVEKSQKAYQEALDIAKDKMQPTHPIRLGLALNFSVFYYEILNTPEHACQLAKQAFDDA 200

Human   200 IAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAGEGGE 244
            |||||||:|:||||||||||||||||||||||. |.|.:..||.:
 Worm   201 IAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDV-GAEDQEQEGNQ 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YWHAZ	NP_003397.1	14-3-3_beta_zeta	2..230	CDD:206758	182/224 (81%)
par-5	NP_001369936.1	14-3-3	6..232	CDD:470464	183/225 (81%)