Protein Alignment YWHAE and 14-3-3epsilon

DIOPT Version :10

• Sequence 1: NP_006752.1
• Gene: YWHAE / 7531
• HGNCID: 12851
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_732309.1
• Gene: 14-3-3epsilon / 42186
• FlyBaseID: FBgn0020238
• Length: 262
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 218/262 - (83%)
• Similarity: 237/262 - (90%)
• Gaps: 10/262 - (3%)

Human     1 MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISS 65
            |.:||:.||:|||||||||||||||:|||||.|||||||||||||||||||||||||||||||:|
  Fly     1 MTERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITS 65

Human    66 IEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHR 130
            |||||||||.|:||:||:.||..||.||:.||.|||:||:|||||.|.:||||||||||||||||
  Fly    66 IEQKEENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHR 130

Human   131 YLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLA 195
            ||||||||:|||:||||||:||||||||||.:|||||||||||||||||||||||||||||||||
  Fly   131 YLAEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLA 195

Human   196 KAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQ--------GDGEEQNKEALQDVED 252
            |||||||||||||||||||||||||||||||||||||||||        ||||.  ||.:|||||
  Fly   196 KAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAGDGEP--KEQIQDVED 258

Human   253 EN 254
            ::
  Fly   259 QD 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YWHAE	NP_006752.1	14-3-3_epsilon	4..233	CDD:206757	201/228 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..255		14/29 (48%)
14-3-3epsilon	NP_732309.1	14-3-3_epsilon	4..233	CDD:206757	201/228 (88%)