Protein Alignment YWHAE and 14-3-3zeta

DIOPT Version :10

• Sequence 1: NP_006752.1
• Gene: YWHAE / 7531
• HGNCID: 12851
• Length: 255
• Species: Homo sapiens
• Sequence 2: NP_476885.2
• Gene: 14-3-3zeta / 36059
• FlyBaseID: FBgn0004907
• Length: 248
• Species: Drosophila melanogaster
• Alignment Length: 239
• Identity: 164/239 - (68%)
• Similarity: 196/239 - (82%)
• Gaps: 2/239 - (0%)

Human     3 DREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIE 67
            |:|:||.:||||||:||||:|.::||.|....|||:.|||||||||||||:||||:|||:|||||
  Fly     5 DKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSIE 69

Human    68 QKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYL 132
            ||.|  ....|.::.||||:.||.||:.||.::|.:|||:|||.|:..||||||.||||||:|||
  Fly    70 QKTE--ASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYL 132

Human   133 AEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKA 197
            ||.|||:.|....::|..||:.|.||:..::.|||||||||||||||||||||||||:||:|||.
  Fly   133 AEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQ 197

Human   198 AFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEE 241
            ||||||||||||:|:||||||||||||||||||||||.|||..|
  Fly   198 AFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAE 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YWHAE	NP_006752.1	14-3-3_epsilon	4..233	CDD:206757	156/228 (68%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..255		5/8 (63%)
14-3-3zeta	NP_476885.2	14-3-3	5..234	CDD:470464	158/230 (69%)