DRSC/TRiP Functional Genomics Resources

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Protein Alignment XPNPEP1 and CG32454

DIOPT Version :10

Sequence 1:NP_001311062.1 Gene:XPNPEP1 / 7511 HGNCID:12822 Length:695 Species:Homo sapiens
Sequence 2:NP_730740.1 Gene:CG32454 / 318037 FlyBaseID:FBgn0260481 Length:534 Species:Drosophila melanogaster


Alignment Length:355 Identity:73/355 - (20%)
Similarity:128/355 - (36%) Gaps:118/355 - (33%)


- Green bases have known domain annotations that are detailed below.


Human   165 LIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRP--------------ERPCKPLLTLGLD 215
            |::||.:..::.|.:|...   :|   :|::|...|.|              .||          
  Fly    33 LVLPTVWPSELTKRIRPLS---VP---DLIEKFSCDAPGGQFATMSEYLRSDPRP---------- 81

Human   216 YTGISWKDKVADLRLKMA--ERNVMWFVVTALDE-------IAWLFNLRGSDVEHNPVF-----F 266
             .|:...|:: ||..||:  :.|.......|..|       .:.:..:.|:|...:..|     |
  Fly    82 -DGVLLPDEI-DLHRKMSLDDLNSYMHAKDAFKEPHRKNRIFSHVLVVAGADSARSYPFRQRPDF 144

Human   267 SY---------AIIGLET------IMLFIDGDRIDA--PSVKEHLLLDLGLEAEYRIQVHPYKSI 314
            .|         |::...:      .:||:..| :|:  .::..|:        .|...|.|...:
  Fly   145 LYLCDCLRPGAALVLTRSRKRNTGALLFLSQD-VDSQLSTIFSHM--------HYVDDVLPLAML 200

Human   315 LSELKALCADLSPREKVW----VSDKASYAVSET-----IPKDH-RCCMPYTPICIAKAVKNSAE 369
            ...|..|..|.||  ::|    .|...|..|.|.     ||..: |..:.||     :.||.|.|
  Fly   201 KKSLLWLLRDHSP--ELWHFYDPSSPVSCIVQEVANEAKIPMGNPRYILQYT-----RTVKTSRE 258

Human   370 SEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAA-DKAEEFRRQQADFVDLSFPTISSTGPN 433
            ...:|||:...|.::.|:.. ...::|:    |::|: |.....|..:.|.      |.:|.|.:
  Fly   259 LRALRRANATAADSMAEVIA-QHHQIPQ----ELAASFDYKCRLRHARPDV------TKTSCGLD 312

Human   434 GAIIHYAPVPETNRTLSLDEVYLIDSGAQY 463
            |                 :.::.:|:|.||
  Fly   313 G-----------------NGLWQMDAGCQY 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
XPNPEP1NP_001311062.1 Creatinase_N 53..197 CDD:480631 7/31 (23%)
Creatinase_N_2 200..369 CDD:465053 45/223 (20%)
APP 372..594 CDD:238518 19/93 (20%)
Peptidase_M24_C 600..>627 CDD:465052
CG32454NP_730740.1 AMP_N 106..223 CDD:198079 22/127 (17%)
APP_MetAP 259..468 CDD:469704 19/95 (20%)
Blue background indicates that the domain is not in the aligned region.

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