DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment WNT9A and wg

DIOPT Version :10

Sequence 1:NP_003386.1 Gene:WNT9A / 7483 HGNCID:12778 Length:365 Species:Homo sapiens
Sequence 2:NP_523502.1 Gene:wg / 34009 FlyBaseID:FBgn0284084 Length:468 Species:Drosophila melanogaster


Alignment Length:433 Identity:137/433 - (31%)
Similarity:199/433 - (45%) Gaps:117/433 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    37 EPLTILPLT-LEPEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFE 100
            ||..|.|:. ::|...:          .|.|||||:.|.:|||...||:..:::..|||.|||..
  Fly    46 EPNNITPIMYMDPAIHS----------TLRRKQRRLVRDNPGVLGALVKGANLAISECQHQFRNR 100

Human   101 RWNCTLEGRYR-----ASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENR 160
            ||||:.....|     ..::.||.:||:|:|||:||.:||::|:|||.|.:|.||||.:....:.
  Fly   101 RWNCSTRNFSRGKNLFGKIVDRGCRETSFIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRSP 165

Human   161 EA------------WQWGGCGDNLKYSSKFVKEFL--GRRSSKDLRARVDFHNNLVGVKVIKAGV 211
            :|            |:||||.||:.:..||.:||:  |.| .::||.:::.|||..|...::|.:
  Fly   166 QANHQAGSVAGVRDWEWGGCSDNIGFGFKFSREFVDTGER-GRNLREKMNLHNNEAGRAHVQAEM 229

Human   212 ETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASG 276
            ...|||||:||||||:|||.:||.|..:|.:||.:::.|.:|..|.:..|..|.|...|....|.
  Fly   230 RQECKCHGMSGSCTVKTCWMRLANFRVIGDNLKARFDGATRVQVTNSLRATNALAPVSPNAAGSN 294

Human   277 AGGSDPL---------------------------------------------------------- 283
            :.||:.|                                                          
  Fly   295 SVGSNGLIIPQSGLVYGEEEERMLNDHMPDILLENSHPISKIHHPNMPSPNSLPQAGQRGGRNGR 359

Human   284 --------------PRTPE--------LVHLDDSPSFCLAG--RFSPGTAGRRCHREK----NCE 320
                          |..||        ||:|:.|||||...  :...||.||:|:...    .|.
  Fly   360 RQGRKHNRYHFQLNPHNPEHKPPGSKDLVYLEPSPSFCEKNLRQGILGTHGRQCNETSLGVDGCG 424

Human   321 SICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTC 363
            .:|||||:.....||...|.|...|||.|:|:.|..::.:|||
  Fly   425 LMCCGRGYRRDEVVVVERCACTFHWCCEVKCKLCRTKKVIYTC 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WNT9ANP_003386.1 Wnt 64..364 CDD:393294 132/405 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 260..287 9/98 (9%)
wgNP_523502.1 Wnt_Wnt1 64..468 CDD:381707 132/405 (33%)

Return to query results.
Submit another query.