Protein Alignment WNT9A and Wnt4

DIOPT Version :10

• Sequence 1: NP_003386.1
• Gene: WNT9A / 7483
• HGNCID: 12778
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 114/325 - (35%)
• Similarity: 184/325 - (56%)
• Gaps: 44/325 - (13%)

Human    59 CDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRGFKETA 123
            |..:...|:|...||::.|:..||.||..::...|:.|||::||||::|.|.:.::.|:.:||||
  Fly   240 CRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLYKETA 304

Human   124 FLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREA--WQWGGCGDNLKYSSKFVKEFL--- 183
            |::|:::|.:||::|:||:.|||.:|:|  .|...||||  :|||||.||||:..:..:.||
  Fly   305 FVHALTAAAMTHSIARACAEGRMTKCSC--GPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLR 367

Human   184 ---GRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKH 245
               |...|:.||     |::.||::.:.:.:...||||||||||:::|||:::|.|:.....|:.
  Fly   368 GGDGDEVSEILR-----HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQ 427

Human   246 KYETAL-KVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPE------LVHLDDSPSFCLAGR 303
            ||..|: |..:..:.....:..:..|:.|.          :.|:      |.:|:.|||:|..
  Fly   428 KYNEAIRKAPNQRSMRQVSSSRMKKPKQRR----------KKPQQSQYTTLYYLETSPSYCAV-- 480

Human   304 FSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRW----CCYVECRQCTQREEVYTCK 364
                |..|:|....||.::|||||:.||  ||.:..:|:.|:    ||.:.|..|.:.|..|.||
  Fly   481 ----TKDRQCLHPDNCGTLCCGRGYTTQ--VVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539

Human   365  364
              Fly   540  539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT9A	NP_003386.1	Wnt	64..364	CDD:393294	111/318 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..287		2/26 (8%)
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	111/318 (35%)