Protein Alignment WNT2B and Wnt10

DIOPT Version :9

• Sequence 1: NP_078613.1
• Gene: WNT2B / 7482
• HGNCID: 12781
• Length: 391
• Species: Homo sapiens
• Sequence 2: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 472
• Identity: 148/472 - (31%)
• Similarity: 206/472 - (43%)
• Gaps: 120/472 - (25%)

Human     9 EAAQLPLRRASAPVPVPSPAAPDGSR---ASARLGLACLLLLLLLTLPARVDTSWWYIGALGARV 70
            |..|||.::........|.::...|.   |:......|.|.|:::.:.| ..|.|.| |....|.
  Fly    12 EQQQLPQQQKQQQEAGSSSSSNSSSNNLVATPATSRHCNLHLIVMIILA-CCTRWLY-GLPDGRA 74

Human    71 ICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLD----RDHTVFGRV 131
            .|.::|||...|.:||.:..|:..:..||....|||||.||:.|||||::|.    ..|.  ..:
  Fly    75 TCRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHA--SSL 137

Human   132 MLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDP-------------------------- 170
            :.:..||:||.:|||:|||.|::.||||||.|..|.|||
  Fly   138 LKKGYRESAFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYL 202

Human   171 -------------YTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNN 222
                         |.|.:...:   :.|||||.|:.:||.::|.|:|.:|| ..|.::.:|||||
  Fly   203 ETNQILTPEEEKKYERSKIASR---WKWGGCSHNMDFGVEYSKLFLDCREK-AGDIQSKINLHNN 263

Human   223 RCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFR---------------------------- 259
            ..||.||...::..|||||:||||.|:|||::..||.
  Fly   264 HAGRIAVSNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVV 328

Human   260 -----------------------------------RTGDYLRRRYDG-AVQVMATQDGANFTAAR 288
                                               .|||...||:|. .|:....|..|:..|||
  Fly   329 VLKRARNKKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAAR 393

Human   289 QGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVT 353
            ..  |...|.|.|:..||::|..|..|...||.||.|::.:..:|||..:|||||:......|..
  Fly   394 MA--RKLETSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAE 456

Human   354 QCECKFHWCCAVRCKEC 370
            :|.|||.|||.|.|:||
  Fly   457 RCHCKFQWCCNVECEEC 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT2B	NP_078613.1	wnt	74..380	CDD:306592	131/404 (32%)
		WNT-core domain	107..379		119/371 (32%)
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	123/391 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152259
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740