Protein Alignment WNT2B and Wnt5

DIOPT Version :9

• Sequence 1: NP_078613.1
• Gene: WNT2B / 7482
• HGNCID: 12781
• Length: 391
• Species: Homo sapiens
• Sequence 2: NP_001285407.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 462
• Identity: 142/462 - (30%)
• Similarity: 198/462 - (42%)
• Gaps: 158/462 - (34%)

Human    72 CDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRDHTVFGRVMLRSS 136
            |.:..||.:.|::.|.::..:|.::..|||..|:|||.||::.||||:|.: |.||||.:...::
  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTN-DETVFGPMTSLAA 611

Human   137 REAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRH-HDQRGDFDWGGCSDNIHYGVRFAK 200
            .|.||::|:::|.|...|.|||..|:|:.|||...:|.:. ||   |:.||||.||:.:..:||.
  Fly   612 PEMAFIHALAAATVTSFIARACRDGQLASCSCSRGSRPKQLHD---DWKWGGCGDNLEFAYKFAT 673

Human   201 AFVDAKEKR-------------------------------------------------------- 209
            .|:|::||.
  Fly   674 DFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTE 738

Human   210 ----------------------------------------------------------------- 209
                                                                             
  Fly   739 AENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRK 803

Human   210 -------------------LKD------------ARALMNLHNNRCGRTAVRRFLKLECKCHGVS 243
                               .||            ||:|||||||..||.||.:..::.|||||||
  Fly   804 NQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVS 868

Human   244 GSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGANFTAARQGYRRATRTDLVYFDNSPDY 308
            |||:|.|||:.||..|..|||||.:|:||.:|...:.|.......| ::..|..||:|.|.|||:
  Fly   869 GSCSLITCWQQLSSIREIGDYLREKYEGATKVKINKRGRLQIKDLQ-FKVPTAHDLIYLDESPDW 932

Human   309 CVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNT 373
            |....|....||.||||.|.|.|.:.|.|:||||||:|..:....:|.|||||||.|:|:.|...
  Fly   933 CRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKV 997

Human   374 VDVHTCK 380
            ::.||||
  Fly   998 LEEHTCK 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT2B	NP_078613.1	wnt	74..380	CDD:306592	139/458 (30%)
		WNT-core domain	107..379		128/424 (30%)
Wnt5	NP_001285407.1	wnt	554..1004	CDD:278536	138/454 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326151at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750