DRSC/TRiP Functional Genomics Resources

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Protein Alignment WNT8B and Wnt6

DIOPT Version :9

Sequence 1:NP_003384.2 Gene:WNT8B / 7479 HGNCID:12789 Length:351 Species:Homo sapiens
Sequence 2:NP_001260188.1 Gene:Wnt6 / 34010 FlyBaseID:FBgn0031902 Length:420 Species:Drosophila melanogaster


Alignment Length:361 Identity:121/361 - (33%)
Similarity:159/361 - (44%) Gaps:95/361 - (26%)


- Green bases have known domain annotations that are detailed below.


Human    46 GAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRSANRETAFVHAISSAGVMYTLTRNCSLGDFD 110
            |...|..||::||...||||  ..|:.|....|...:|||.||:||::|||.|.:|:.|::|...
  Fly    63 GINLGFRECEFQFRNRRWNC--TVLRKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLV 125

Human   111 NCGCDDSRNGQLGGQ-------------------------------------------------- 125
            .|.||.:...:.|||                                                  
  Fly   126 ECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIA 190

Human   126 ------------------------------GWLWGGCSDNVGFGEAISKQFVDALETGQ--DARA 158
                                          .|.||||||||.||...|:.|:||.:..:  |...
  Fly   191 PVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGT 255

Human   159 AMNLHNNEAGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDLLQG 223
            .:..|||.|||.|::..|:..|||||:|||||.:||||::|.||||...|:::|.:|.|| .|:.
  Fly   256 LVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKV-TLRN 319

Human   224 AGNSAAGRGAIADTFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRRGRALGRWERRSCR 288
            .|||.......|   |..:..:||..:||||:|..|...|.|||:||||........|     |.
  Fly   320 DGNSFMPESPHA---RPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDR-----CD 376

Human   289 RLCGDCGLAVEERRAETVSSCNCKFHWCCAVRCEQC 324
            |||  |......|..|..::|.|.|.|||.|.||:|
  Fly   377 RLC--CNRGHTRRIVEEQTNCKCVFKWCCEVTCEKC 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WNT8BNP_003384.2 WNT1 23..333 CDD:128408 121/361 (34%)
Wnt6NP_001260188.1 wnt 41..419 CDD:278536 121/361 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG45757
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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