Protein Alignment WNT8B and Wnt5

DIOPT Version :9

• Sequence 1: NP_003384.2
• Gene: WNT8B / 7479
• HGNCID: 12789
• Length: 351
• Species: Homo sapiens
• Sequence 2: NP_001285407.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 448
• Identity: 120/448 - (26%)
• Similarity: 167/448 - (37%)
• Gaps: 171/448 - (38%)

Human    42 SVAAGAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRS-ANRETAFVHAISSAGVMYTLTRNCS 105
            :::.||::.|:||::||...|||| ......:..|.:.| |..|.||:||:::|.|...:.|.|.
  Fly   571 AISRGARAAIQECQFQFKNRRWNC-STTNDETVFGPMTSLAAPEMAFIHALAAATVTSFIARACR 634

Human   106 LGDFDNCGCD-DSRNGQLGGQGWLWGGCSDNVGFGEAISKQFVDA--LETGQD------------ 155
            .|...:|.|. .||..|| ...|.||||.||:.|....:..|:|:  .||.::
  Fly   635 DGQLASCSCSRGSRPKQL-HDDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEIN 698

Human   156 ----------------------------------------------------------------- 155
                                                                             
  Fly   699 KNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKE 763

Human   156 ----------------------------------------------------------------- 155
                                                                             
  Fly   764 ILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGI 828

Human   156 ---------ARAAMNLHNNEAGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEK 211
                     ||:.||||||||||:||....:.|||||||||||:..|||.||...||:|.:|:||
  Fly   829 LPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREK 893

Human   212 YHAALKVDLLQGAGNSAAGRGAIAD-TFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRR 275
            |..|.||.:      :..||..|.| .|:..:..:|::|::|||:|..:..|...||.||.|.:.
  Fly   894 YEGATKVKI------NKRGRLQIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKN 952

Human   276 GRALGRWERRSCRRLCGDCGLAVEERRAETVSSCNCKFHWCCAVRCEQCRRRVTKYFC 333
            ...|     .||..||  ||.....:.......|||||||||.|:||.|.:.:.::.|
  Fly   953 SSGL-----ESCAILC--CGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLEEHTC 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT8B	NP_003384.2	WNT1	23..333	CDD:128408	119/446 (27%)
Wnt5	NP_001285407.1	wnt	554..1004	CDD:278536	120/448 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152276
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740