Protein Alignment WNT7B and Wnt10

DIOPT Version :9

• Sequence 1: XP_011528668.1
• Gene: WNT7B / 7477
• HGNCID: 12787
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 409
• Identity: 138/409 - (33%)
• Similarity: 194/409 - (47%)
• Gaps: 100/409 - (24%)

Human    42 CNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINECQYQFRFGRWNCSALGEKT---VFGQELRV 103
            |..:|||...|..:|....|......||..|.|.|||.||::.|||||:|..|:   .....|:.
  Fly    76 CRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHASSLLKK 140

Human   104 GSREAAFTYAITAAGVAHAVTAACSQGNLSNCGC-----------------DREKQGYY-----N 146
            |.||:||.:||:||||||:|..|||||.|.:|||                 |:||:.:.     |
  Fly   141 GYRESAFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLETN 205

Human   147 Q---------------AEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEAGRKVL 196
            |               |..|||||||.::.:|:::|:.|:|.||...:.:..:|||||.|||..:
  Fly   206 QILTPEEEKKYERSKIASRWKWGGCSHNMDFGVEYSKLFLDCREKAGDIQSKINLHNNHAGRIAV 270

Human   197 EDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVE-----------VVRASR- 249
            .:.|:..|||||:||||..||||.:.|.|..||.:||.::..|:.|:           |::.:|
  Fly   271 SNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRARN 335

Human   250 ----------------------------------------------LRQPTFLRIKQLRSYQKPM 268
                                                          .|||:  ..|......:.:
  Fly   336 KKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPS--ADKNAARMARKL 398

Human   269 ETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFH 333
            ||.|.|.::|||:||.|......||.||.|||.:..:|||.::|||||::.....:..:|:|||.
  Fly   399 ETSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCKFQ 463

Human   334 WCCFVKCNTCSERTEVFTC 352
            |||.|:|..|.....:..|
  Fly   464 WCCNVECEECHVEEWISIC 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT7B	XP_011528668.1	wnt_Wnt7b	36..353	CDD:381724	138/409 (34%)
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	129/385 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152265
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740