Protein Alignment WNT7B and Wnt4

DIOPT Version :10

• Sequence 1: NP_001397735.1
• Gene: WNT7B / 7477
• HGNCID: 12787
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 108/331 - (32%)
• Similarity: 174/331 - (52%)
• Gaps: 50/331 - (15%)

Human    42 CNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINECQYQFRFGRWNCS--ALGEKTVFGQELRVG 104
            |..:|. ..||...|:........:.|..::....|:.|||:.|||||  ..|::.:|.:..
  Fly   240 CRYMPA-TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY--- 300

Human   105 SREAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRR 169
             :|.||.:|:|||.:.|::..||::|.::.|.|..:|  :..:|:.::||||:.::::|...:|.
  Fly   301 -KETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKK--HNREAQDFQWGGCNDNLKHGKRVTRS 362

Human   170 FVDAR-----EIKKNARRLMNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVG 229
            |:|.|     |:.:..|     |::|.|.:.:..:|..:||||||||||:.||||..:..|....
  Fly   363 FLDLRGGDGDEVSEILR-----HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATA 422

Human   230 HLLKEKYNAAVQ-------VEVVRASRLRQPTFLRIKQLRSYQKPME---TDLVYIEKSPNYCEE 284
            .||::|||.|::       :..|.:||:::|     ||.|  :||.:   |.|.|:|.||:||
  Fly   423 TLLRQKYNEAIRKAPNQRSMRQVSSSRMKKP-----KQRR--KKPQQSQYTTLYYLETSPSYC-- 478

Human   285 DAATGSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFH--WCCFVKCNTCSERT 347
                  ..|:.|.|..    .|.|.|:||||||.|....:|.:|.|:|:  .||.:.|:.|....
  Fly   479 ------AVTKDRQCLH----PDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLE 533

Human   348 EVFTCK 353
            ..:.||
  Fly   534 NKYFCK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT7B	NP_001397735.1	wnt_Wnt7b	36..353	CDD:381724	106/329 (32%)
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	104/324 (32%)