DRSC/TRiP Functional Genomics Resources

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Protein Alignment WNT7A and wntD

DIOPT Version :9

Sequence 1:NP_004616.2 Gene:WNT7A / 7476 HGNCID:12786 Length:349 Species:Homo sapiens
Sequence 2:NP_650272.1 Gene:wntD / 41633 FlyBaseID:FBgn0038134 Length:309 Species:Drosophila melanogaster


Alignment Length:310 Identity:84/310 - (27%)
Similarity:128/310 - (41%) Gaps:62/310 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    61 VIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGK-ELKVGSREAAFTYAIIAAGVAHAITAACT 124
            :.|:|.:..||.||..|:..||||.:........| |....:||..:..||..|.:.|.:|..|.
  Fly    39 ITGKGLKQALDSCQQSFQWQRWNCPSQDFVQKNSKPEENSPNREDVYVAAISMAAIVHTLTKDCA 103

Human   125 QGNLSDCGCDKEKQG------------QYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNAR 177
            .|.::.|||.:....            ||.:..|   .|..|     ||                
  Fly   104 NGVIAGCGCTENALNVPCAHEPTKALEQYEKHFG---SGSGA-----IG---------------- 144

Human   178 TLMNLHNNEAGRKILEENMKLECKCH---GVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVE 239
                 ||......:|:.:::.||:|.   .|.|.|..:.|...|..|..:...|...|::|:.:|
  Fly   145 -----HNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDDAIQLE 204

Human   240 PVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNK----TAPQ 300
              .||.|.:..:..|        |:|: ||:::.||||||.|......||:||.|:|    :..:
  Fly   205 --GASSNLKIMWQNI--------PLDS-LVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLEE 258

Human   301 ASGCDLMCCGRGYNTH-QYARV-WQCNCKFHWCCYVKCNTCSERTEMYTC 348
            ...|..:|...||... |:.|. .:||||..|...::|:.|.:....|:|
  Fly   259 RLSCQQLCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WNT7ANP_004616.2 Wnt_Wnt7a 32..349 CDD:381723 84/310 (27%)
Disordered linker. /evidence=ECO:0000269|PubMed:30026314 238..266 6/27 (22%)
wntDNP_650272.1 wnt 41..308 CDD:302926 83/306 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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