Protein Alignment WNT7A and wntD

DIOPT Version :10

• Sequence 1: NP_004616.2
• Gene: WNT7A / 7476
• HGNCID: 12786
• Length: 349
• Species: Homo sapiens
• Sequence 2: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Alignment Length: 310
• Identity: 84/310 - (27%)
• Similarity: 128/310 - (41%)
• Gaps: 62/310 - (20%)

Human    61 VIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGK-ELKVGSREAAFTYAIIAAGVAHAITAACT 124
            :.|:|.:..||.||..|:..||||.:........| |....:||..:..||..|.:.|.:|..|.
  Fly    39 ITGKGLKQALDSCQQSFQWQRWNCPSQDFVQKNSKPEENSPNREDVYVAAISMAAIVHTLTKDCA 103

Human   125 QGNLSDCGCDKEKQG------------QYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNAR 177
            .|.::.|||.:....            ||.:..|   .|..|     ||
  Fly   104 NGVIAGCGCTENALNVPCAHEPTKALEQYEKHFG---SGSGA-----IG---------------- 144

Human   178 TLMNLHNNEAGRKILEENMKLECKCH---GVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVE 239
                 ||......:|:.:::.||:|.   .|.|.|..:.|...|..|..:...|...|::|:.:|
  Fly   145 -----HNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVAVLKPFEAIAQDLLQMYDDAIQLE 204

Human   240 PVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNK----TAPQ 300
              .||.|.:..:..|        |:|: ||:::.||||||.|......||:||.|:|    :..:
  Fly   205 --GASSNLKIMWQNI--------PLDS-LVFMQDSPNYCERDATGLWKGTRGRQCSKDGSGSLEE 258

Human   301 ASGCDLMCCGRGYNTH-QYARV-WQCNCKFHWCCYVKCNTCSERTEMYTC 348
            ...|..:|...||... |:.|. .:||||..|...::|:.|.:....|:|
  Fly   259 RLSCQQLCRVCGYRVRSQHVRTERRCNCKLVWGFRLQCDVCVQLERQYSC 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT7A	NP_004616.2	Wnt_Wnt7a	32..349	CDD:381723	84/310 (27%)
		Disordered linker. /evidence=ECO:0000269|PubMed:30026314	238..266		6/27 (22%)
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	84/310 (27%)