Protein Alignment WNT7A and wg

DIOPT Version :10

• Sequence 1: NP_004616.2
• Gene: WNT7A / 7476
• HGNCID: 12786
• Length: 349
• Species: Homo sapiens
• Sequence 2: NP_523502.1
• Gene: wg / 34009
• FlyBaseID: FBgn0284084
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 404
• Identity: 138/404 - (34%)
• Similarity: 190/404 - (47%)
• Gaps: 99/404 - (24%)

Human    44 LAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALG---ERTVFGKELKVGSREAA 105
            |..:||.:.:..|..:..:.:|:.:.:.|||.||||.|||||...   .:.:|||.:..|.||.:
  Fly    64 LRRKQRRLVRDNPGVLGALVKGANLAISECQHQFRNRRWNCSTRNFSRGKNLFGKIVDRGCRETS 128

Human   106 FTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQG---QYHRDEG-------WKWGGCSADIRYGI 160
            |.|||.:|.|.|:|..||::|.:..|.||...|.   |.:...|       |:|||||.:|.:|.
  Fly   129 FIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRSPQANHQAGSVAGVRDWEWGGCSDNIGFGF 193

Human   161 GFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELG 225
            .|::.|||..|..:|.|..||||||||||..::..|:.||||||:|||||.||||..|..||.:|
  Fly   194 KFSREFVDTGERGRNLREKMNLHNNEAGRAHVQAEMRQECKCHGMSGSCTVKTCWMRLANFRVIG 258

Human   226 YVLKDKYNEAVHVE---PVRASRNKRPT------------------------------------- 250
            ..||.:::.|..|:   .:||:....|.
  Fly   259 DNLKARFDGATRVQVTNSLRATNALAPVSPNAAGSNSVGSNGLIIPQSGLVYGEEEERMLNDHMP 323

Human   251 --FLKIKKPLS--------------------------------------------YRKPMDTDLV 269
              .|:...|:|                                            ::.|...|||
  Fly   324 DILLENSHPISKIHHPNMPSPNSLPQAGQRGGRNGRRQGRKHNRYHFQLNPHNPEHKPPGSKDLV 388

Human   270 YIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYV 334
            |:|.||::||::...|.:||.||.||:|:....||.||||||||...:...|.:|.|.|||||.|
  Fly   389 YLEPSPSFCEKNLRQGILGTHGRQCNETSLGVDGCGLMCCGRGYRRDEVVVVERCACTFHWCCEV 453

Human   335 KCNTCSERTEMYTC 348
            ||..|..:..:|||
  Fly   454 KCKLCRTKKVIYTC 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT7A	NP_004616.2	Wnt_Wnt7a	32..349	CDD:381723	138/404 (34%)
		Disordered linker. /evidence=ECO:0000269|PubMed:30026314	238..266		8/113 (7%)
wg	NP_523502.1	Wnt_Wnt1	64..468	CDD:381707	138/404 (34%)