Protein Alignment WNT7A and Wnt5

DIOPT Version :9

• Sequence 1: NP_004616.2
• Gene: WNT7A / 7476
• HGNCID: 12786
• Length: 349
• Species: Homo sapiens
• Sequence 2: NP_001285407.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 466
• Identity: 136/466 - (29%)
• Similarity: 185/466 - (39%)
• Gaps: 163/466 - (34%)

Human    38 CNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSR 102
            |....||:..|:..|......:..|..|::..:.||||||:|.|||||...:.||||....:.:.
  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAP 612

Human   103 EAAFTYAIIAAGVAHAITAACTQGNLSDCGCDK-EKQGQYHRDEGWKWGGCSADIRYGIGFAKVF 166
            |.||.:|:.||.|...|..||..|.|:.|.|.: .:..|.|.|  ||||||..::.:...||..|
  Fly   613 EMAFIHALAAATVTSFIARACRDGQLASCSCSRGSRPKQLHDD--WKWGGCGDNLEFAYKFATDF 675

Human   167 VDARE---------------------------------IKQN----------------------- 175
            :|:||                                 ||:|
  Fly   676 IDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAE 740

Human   176 ----------------------------------------------------------------- 175
                                                                             
  Fly   741 NSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQ 805

Human   176 --------------------------------ARTLMNLHNNEAGRKILEENMKLECKCHGVSGS 208
                                            ||:|||||||||||:.:.:..::.|||||||||
  Fly   806 RAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGS 870

Human   209 CTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEK 273
            |:..|||..|...||:|..|::||..|..|:     .|||.. |:| |.|.::.|...||:|:::
  Fly   871 CSLITCWQQLSSIREIGDYLREKYEGATKVK-----INKRGR-LQI-KDLQFKVPTAHDLIYLDE 928

Human   274 SPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNT 338
            ||::|.........||.||.|:|.:.....|.::||||||||.......:|||||||||.|||..
  Fly   929 SPDWCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEV 993

Human   339 CSERTEMYTCK 349
            |::..|.:|||
  Fly   994 CTKVLEEHTCK 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT7A	NP_004616.2	Wnt_Wnt7a	32..349	CDD:381723	134/464 (29%)
		Disordered linker. /evidence=ECO:0000269|PubMed:30026314	238..266		9/27 (33%)
Wnt5	NP_001285407.1	wnt	554..1004	CDD:278536	132/458 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152261
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326151at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750