DRSC/TRiP Functional Genomics Resources

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Protein Alignment WNT3 and wntD

DIOPT Version :9

Sequence 1:NP_110380.1 Gene:WNT3 / 7473 HGNCID:12782 Length:355 Species:Homo sapiens
Sequence 2:NP_650272.1 Gene:wntD / 41633 FlyBaseID:FBgn0038134 Length:309 Species:Drosophila melanogaster


Alignment Length:337 Identity:88/337 - (26%)
Similarity:133/337 - (39%) Gaps:70/337 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    34 QYTSLGSQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSL 98
            |||.. ..||....|.|                    :|:|..:..||..|:.:||||.:.|...
  Fly    26 QYTQF-QAPLSWEDITG--------------------KGLKQALDSCQQSFQWQRWNCPSQDFVQ 69

Human    99 AIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDAD 163
            ....|..:...||..:|.||:.|.:...:|:.||.|  .|.||               ||:|:| 
  Fly    70 KNSKPEENSPNREDVYVAAISMAAIVHTLTKDCANG--VIAGC---------------GCTENA- 116

Human   164 FGVLVSREFADARENRP---DARSAMNKHNNEAGRTTILDHMHLKCKCH---GLSGSCEVKTCWW 222
            ..|..:.|...|.|...   .:.|....||.......:...:..:|:|.   .:.|.|:.:.|..
  Fly   117 LNVPCAHEPTKALEQYEKHFGSGSGAIGHNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVA 181

Human   223 AQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYSLFKPPTERDLVYYENSPNFCEPN 287
            ....|.||...|...||.|.::        .|....|:..:.  ..|.: .||:.::|||:|| .
  Fly   182 VLKPFEAIAQDLLQMYDDAIQL--------EGASSNLKIMWQ--NIPLD-SLVFMQDSPNYCE-R 234

Human   288 PETGSF-GTRDRTCNVTSHG-ID---GCDLLC--CG---RGHNTRTEKRKEKCHCIFHWCCYVSC 342
            ..||.: |||.|.|:....| ::   .|..||  ||   |..:.|||:|   |:|...|...:.|
  Fly   235 DATGLWKGTRGRQCSKDGSGSLEERLSCQQLCRVCGYRVRSQHVRTERR---CNCKLVWGFRLQC 296

Human   343 QECIRIYDVHTC 354
            ..|:::...::|
  Fly   297 DVCVQLERQYSC 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WNT3NP_110380.1 Wnt_Wnt3_Wnt3a 42..355 CDD:381709 85/329 (26%)
wntDNP_650272.1 wnt 41..308 CDD:302926 81/319 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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