Protein Alignment WNT3 and wntD

DIOPT Version :10

• Sequence 1: NP_110380.1
• Gene: WNT3 / 7473
• HGNCID: 12782
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_650272.1
• Gene: wntD / 41633
• FlyBaseID: FBgn0038134
• Length: 309
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 88/337 - (26%)
• Similarity: 133/337 - (39%)
• Gaps: 70/337 - (20%)

Human    34 QYTSLGSQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSL 98
            |||.. ..||....|.|                    :|:|..:..||..|:.:||||.:.|...
  Fly    26 QYTQF-QAPLSWEDITG--------------------KGLKQALDSCQQSFQWQRWNCPSQDFVQ 69

Human    99 AIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDAD 163
            ....|..:...||..:|.||:.|.:...:|:.||.|  .|.||               ||:|:|
  Fly    70 KNSKPEENSPNREDVYVAAISMAAIVHTLTKDCANG--VIAGC---------------GCTENA- 116

Human   164 FGVLVSREFADARENRP---DARSAMNKHNNEAGRTTILDHMHLKCKCH---GLSGSCEVKTCWW 222
            ..|..:.|...|.|...   .:.|....||.......:...:..:|:|.   .:.|.|:.:.|..
  Fly   117 LNVPCAHEPTKALEQYEKHFGSGSGAIGHNRRVVGALLQRSLEQECRCKQPGAVQGECQEEECVA 181

Human   223 AQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYSLFKPPTERDLVYYENSPNFCEPN 287
            ....|.||...|...||.|.::        .|....|:..:.  ..|.: .||:.::|||:|| .
  Fly   182 VLKPFEAIAQDLLQMYDDAIQL--------EGASSNLKIMWQ--NIPLD-SLVFMQDSPNYCE-R 234

Human   288 PETGSF-GTRDRTCNVTSHG-ID---GCDLLC--CG---RGHNTRTEKRKEKCHCIFHWCCYVSC 342
            ..||.: |||.|.|:....| ::   .|..||  ||   |..:.|||:|   |:|...|...:.|
  Fly   235 DATGLWKGTRGRQCSKDGSGSLEERLSCQQLCRVCGYRVRSQHVRTERR---CNCKLVWGFRLQC 296

Human   343 QECIRIYDVHTC 354
            ..|:::...::|
  Fly   297 DVCVQLERQYSC 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT3	NP_110380.1	Wnt_Wnt3_Wnt3a	42..355	CDD:381709	85/329 (26%)
wntD	NP_650272.1	Wnt_Wnt8	28..309	CDD:381714	86/335 (26%)