Protein Alignment WNT2 and Wnt6

DIOPT Version :9

• Sequence 1: NP_003382.1
• Gene: WNT2 / 7472
• HGNCID: 12780
• Length: 360
• Species: Homo sapiens
• Sequence 2: NP_001260188.1
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Alignment Length: 419
• Identity: 136/419 - (32%)
• Similarity: 201/419 - (47%)
• Gaps: 93/419 - (22%)

Human    15 LLTWLTPEVNSSWWYMRATGGS----SRVMCDNVPGLVSSQRQLCHRHPDVM--RAISQGVAEWT 73
            :|.:..|.....|    |.|.:    ..:||.....|.....::| ||...:  ..|..|:....
  Fly     9 ILIFAMPMTGFGW----AEGTNILLDPNLMCKKTRRLRGKLAEIC-RHDSALLKEIIINGINLGF 68

Human    74 AECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCD 138
            .||:.|||..||||..|.:.   ..::|:|.|||:.||.||::|||.:|:|:||:.|::..||||
  Fly    69 RECEFQFRNRRWNCTVLRKS---MRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCD 130

Human   139 P----------------------------------------------KKMGSA------------ 145
            .                                              .:|.:|
  Fly   131 KAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHR 195

Human   146 --------------------KDSKGIFDWGGCSDNIDYGIKFARAFVDAKERKGK-DARALMNLH 189
                                |..:|.::|||||||:::|::.:|.|:|||:|:.: |...|:..|
  Fly   196 GGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFH 260

Human   190 NNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFT 254
            ||.|||.|::..::.||||||:|||||::||||.|..||:....|..:|:.|.:|.:..||..|.
  Fly   261 NNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLRNDGNSFM 325

Human   255 VANERFKKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVT 319
            ..:...:...|..||:.::|||:|..:.:.|:|||.||.||:||.|.|.|:.:||.||:....|.
  Fly   326 PESPHARPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVE 390

Human   320 RMTKCGCKFHWCCAVRCQDCLEALDVHTC 348
            ..|.|.|.|.|||.|.|:.|||...|:||
  Fly   391 EQTNCKCVFKWCCEVTCEKCLEHRAVNTC 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT2	NP_003382.1	wnt	43..349	CDD:306592	129/387 (33%)
Wnt6	NP_001260188.1	wnt	41..419	CDD:278536	127/381 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810