Protein Alignment WNT1 and Wnt10

DIOPT Version :9

• Sequence 1: NP_005421.1
• Gene: WNT1 / 7471
• HGNCID: 12774
• Length: 370
• Species: Homo sapiens
• Sequence 2: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 394
• Identity: 132/394 - (33%)
• Similarity: 173/394 - (43%)
• Gaps: 99/394 - (25%)

Human    64 LSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPT----APGPHLFGKIVNRGCRET 124
            |::.|..|..:...:..:...||..|:|||:.||:..||||.:    :..||. ..::.:|.||:
  Fly    82 LTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHA-SSLLKKGYRES 145

Human   125 AFIFAITSAGVTHSVARSCSEGSIESCTCD----------------------------------- 154
            ||.|||::|||.|||||:||:|.:.||.||
  Fly   146 AFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLETNQILTP 210

Human   155 -----YRRRGPGGPDWHWGGCSDNIDFGRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEM 214
                 | .|......|.|||||.|:|||..:.:.|:|..||..|::..:|||||.|||..|.:.|
  Fly   211 EEEKKY-ERSKIASRWKWGGCSHNMDFGVEYSKLFLDCREKAGDIQSKINLHNNHAGRIAVSNNM 274

Human   215 RQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGA-------------------SRVLYGN 260
            ...||||||||||.::|||...|....||.||:.:|..|                   :|....|
  Fly   275 EFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRARNKKSN 339

Human   261 RGSNRASRAELLRLEPEDPAH----------------------KPPSPH------------DLVY 291
            .||...|.:..|........|                      :.||..            .|.|
  Fly   340 GGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAARMARKLETSLFY 404

Human   292 FEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVS 356
            :::|||||.........||.||.||.::...|||..|||||||....||..|||:|.|.|||:|.
  Fly   405 YQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCKFQWCCNVE 469

Human   357 CRNC 360
            |..|
  Fly   470 CEEC 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WNT1	NP_005421.1	Wnt_Wnt1	64..370	CDD:381707	132/394 (34%)
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	127/385 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48513
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820