Protein Alignment NSD2 and CG4565

DIOPT Version :10

• Sequence 1: NP_001427822.1
• Gene: NSD2 / 7468
• HGNCID: 12766
• Length: 1398
• Species: Homo sapiens
• Sequence 2: NP_001097743.1
• Gene: CG4565 / 41303
• FlyBaseID: FBgn0037841
• Length: 269
• Species: Drosophila melanogaster
• Alignment Length: 234
• Identity: 74/234 - (31%)
• Similarity: 107/234 - (45%)
• Gaps: 59/234 - (25%)

Human  1049 CNCKPTDENP--CGF---------DSECLNRML---MFECHPQVCPAGEFCQNQCFTKRQY--PE 1097
            |:||...||.  |..         .||.:.|..   :.||: .:|   :.|:|.|..:..|  |.
  Fly    50 CHCKGACENSEVCAHGGQYEFTEDGSELILRNSANPVIECN-DMC---KCCRNTCSNRLVYSGPR 110

Human  1098 TKIIKTD-----GKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHEND----ITHFYML 1153
            ..:...|     .||....||  |.||.::.||.|||:...|..:|:   |:|:    :.:..:|
  Fly   111 KHLEIFDSPVYGSKGLRTTAK--ITKGGYICEYAGELLTVPEARSRL---HDNEKLGLMNYILVL 170

Human  1154 ---TIDKDR---IIDAGPKGNYSRFMNHSCQPNCETLKWTVNGD-TRVGLFAVCDIPAGTELTFN 1211
               |.||.:   |:|...:||..|::||||:|||......::.. .::|:||..||.|..||.|:
  Fly   171 NEYTSDKKQQVTIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEELCFH 235

Human  1212 YNLDCLGNE---------KTVCRCGASNCSGFLGDRPKT 1241
            |     |.|         || |.||||.|:||:   |.|
  Fly   236 Y-----GGEGQYKKMTGGKT-CLCGASKCTGFM---PNT 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NSD2	NP_001427822.1	None
CG4565	NP_001097743.1	SET_SETMAR	16..267	CDD:380942	74/234 (32%)