Protein Alignment WEE1 and Wee1

DIOPT Version :9

• Sequence 1: NP_003381.1
• Gene: WEE1 / 7465
• HGNCID: 12761
• Length: 646
• Species: Homo sapiens
• Sequence 2: NP_001012760.1
• Gene: Wee1 / 308937
• RGDID: 1307895
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 592/648 - (91%)
• Similarity: 602/648 - (92%)
• Gaps: 4/648 - (0%)

Human     1 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPA 65
            |||||||||||.|||.|||:|||||||||.||| |||||||||||||||||||||||||||||.|
  Rat     1 MSFLSRQQPPPTRRAAAACSLRQKLIFSPGSDC-EEEEEEEEEGSGHSTGEDSAFQEPDSPLPSA 64

Human    66 RSPTEPGPE-RRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPA 129
            |||.|...| ||||||..|.|||||||||||.|...||..||||||||||||||||||||||||.
  Rat    65 RSPAEAEAERRRRSPGAEPSSPGELEEDLLLRGGGGGAQAAGGGAEGDSWEEEGFGSSSPVKSPT 129

Human   130 APYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSL 194
            ..||||||||||||||||||||||||..||.:...||:||:|.||||||||||||||||||||||
  Rat   130 TAYFLGSSFSPVRCGGPGDASPRGCGVPRAMDDPCSPQPDYPSTPPHKTFRKLRLFDTPHTPKSL 194

Human   195 LSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYW 259
            |||||.||||||||||||||||||||||||||.||||||||||||||.::||||||||.|||.|:
  Rat   195 LSKARVIDSSSVKLRGSSLFMDTEKSGKREFDTRQTPQVNINPFTPDPVMLHSSGQCRGRKRAYF 259

Human   260 NDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCI 324
            ||| .|||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   260 NDS-SEDMEASDYEFEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCI 323

Human   325 YAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAIS 389
            ||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||:|
  Rat   324 YAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYFSAWAEDDHMLIQNEYCNGGSLADAVS 388

Human   390 ENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWAS 454
            ||||:||||.|||||||||||||||||||||||||||||||||||||||||||.|||||||||.|
  Rat   389 ENYRVMSYFTEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAVSEEGDEDDWIS 453

Human   455 NKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRN 519
            ||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||
  Rat   454 NKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYSHLPKADIFALALTVVCAAGAEPLPRN 518

Human   520 GDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIEL 584
            ||||||||||||||||||||||.|||||||||||||||||||.||||||||||||||||||||||
  Rat   519 GDQWHEIRQGRLPRIPQVLSQELTELLKVMIHPDPERRPSAMVLVKHSVLLSASRKSAEQLRIEL 583

Human   585 NAEKFKNSLLQKELKKAQM-AKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY 646
            ||||||||||||||||||| ||.|||||||.||||||||||||||||||||||||||||||||
  Rat   584 NAEKFKNSLLQKELKKAQMAAKVAAEERALLTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WEE1	NP_003381.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..181		147/180 (82%)
		PTKc_Wee1a	293..568	CDD:271040	265/274 (97%)
		Pkinase	299..569	CDD:278497	260/269 (97%)
Wee1	NP_001012760.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..175		118/148 (80%)
		PTKc_Wee1a	292..567	CDD:271040	265/274 (97%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83680347
Domainoid	1	1.000	533	1.000	Domainoid score	I6235
eggNOG	1	0.900	-	-		E1_KOG0601
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31152
Inparanoid	1	1.050	1163	1.000	Inparanoid score	I4302
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG46922
OrthoDB	1	1.010	-	-		D1063695at2759
OrthoFinder	1	1.000	-	-		FOG0003577
OrthoInspector	1	1.000	-	-		oto138757
orthoMCL	1	0.900	-	-		OOG6_104316
Panther	1	1.100	-	-	LDO	PTHR11042
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1559
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	18.270