Protein Alignment VRK1 and Asator

DIOPT Version :9

• Sequence 1: XP_006720310.1
• Gene: VRK1 / 7443
• HGNCID: 12718
• Length: 420
• Species: Homo sapiens
• Sequence 2: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 124/492 - (25%)
• Similarity: 199/492 - (40%)
• Gaps: 140/492 - (28%)

Human     2 PRVKAAQAGR---------QSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLA-DM 56
            ||.:.|.|.:         :.|.|....:....|.::    |:.|||...||.||||.||.. |:
  Fly   133 PRNQVAVAAKDGILVDVKAKESVKMTSEDLLQPGHVV----KERWKVVRKIGGGGFGEIYEGQDL 193

Human    57 NSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYL----GVPKYWGSG 117
            .:.|.|      .:|||               .|.:|:|:.| :....||.|    .|.::.|.|
  Fly   194 ITREQV------ALKVE---------------SARQPKQVLK-MEVAVLKKLQGKEHVCRFIGCG 236

Human   118 LHDKNGKSYRFMIMDRFGSDLQKIYEANAK-RFSRKTVLQLSLRILDILEYIHEHEYVHGDIKAS 181
            .:|:    :.:::|...|.:|.::..|..: .||..|.|:|.|:||..:|.||...::|.|||.|
  Fly   237 RNDR----FNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPS 297

Human   182 NL---LLNYKNPDQVYLVDYGLAYRY--------CPEGVHKEYKEDPKRCHDGTIEFTSIDAHNG 235
            |.   .|.| |..:||::|:|||.:|        ||...         ....||:.:.||:||..
  Fly   298 NFSVGRLPY-NCRRVYMLDFGLARQYTTGTGEVRCPRAA---------AGFRGTVRYASINAHRN 352

Human   236 VAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA 300
            ....|..||..|.|.:::::.|.|||. .:||.:.|..:|.:|...|..        |:.|.::.
  Fly   353 REMGRHDDLWSLFYMLVEFVNGQLPWR-KIKDKEQVGLTKEKYDHRILL--------KHLPSDLK 408

Human   301 KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDG-----KLDLSVVEN-------------- 346
            :::|.::.|.|.::|.|..|..:..:.:|..|.|:..     |:|.:.:.|
  Fly   409 QFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIKSD 473

Human   347 ---GGLKAKTITK---------KRKKEIEE------------------------------SKEPG 369
               |.:...|:..         :::.|||.                              |.||.
  Fly   474 YMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKNCNATSLAQPAKGSGEPM 538

Human   370 VEDTEWSNTQ--TEEAIQTRS--EESQGAIHRSMSQP 402
            |:....:|.|  |.:.:|.:|  ..||.||....|.|
  Fly   539 VQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAP 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VRK1	XP_006720310.1	STKc_VRK1	26..326	CDD:271024	92/316 (29%)
		S_TKc	37..293	CDD:214567	82/272 (30%)
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	90/305 (30%)
		S_TKc	173..414	CDD:214567	85/285 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810