Protein Alignment VRK1 and dco

DIOPT Version :10

• Sequence 1: XP_047287708.1
• Gene: VRK1 / 7443
• HGNCID: 12718
• Length: 422
• Species: Homo sapiens
• Sequence 2: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 99/322 - (30%)
• Similarity: 157/322 - (48%)
• Gaps: 41/322 - (12%)

Human    38 EWKVGLPIGQGGFGCIYL-ADMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKW 101
            ::::|..||.|.||.||| ..:|:.|.|.....|:....|.    |..|.|||      :.:|..
  Fly     8 KYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQ----LHIESKFY------KTMQGG 62

Human   102 IRTRKLKYLGVPK-YWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILD 165
            |        |:|: .|.....|     |..|:|:..|..|:.::...::|||.||||.|:.:::.
  Fly    63 I--------GIPRIIWCGSEGD-----YNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMIS 114

Human   166 ILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLA--YRYCPEGVHKEYKEDPKRCHDGTI 227
            .::|||..:::|.|||..|.|:.. |..:.||::|:|||  :|......|..|:|:...  .||.
  Fly   115 RIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNL--TGTA 177

Human   228 EFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWED----NLKDPKYVRDSKIRYRENIASLM 288
            .:.||:.|.|:..|||.|||.|||.::.:..|.|||:.    | |..||.|.|:.:...:|..|
  Fly   178 RYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAAN-KRQKYERISEKKLSTSIVVL- 240

Human   289 DKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGG 350
              |   |..|.|...|:...:.:.:.::|.|.:||.:.......:|...|...|.::::.||
  Fly   241 --C---KGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGG 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VRK1	XP_047287708.1	STKc_VRK1	28..328	CDD:271024	94/298 (32%)
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	94/305 (31%)