Protein Alignment VRK1 and CG9962

DIOPT Version :10

• Sequence 1: XP_047287708.1
• Gene: VRK1 / 7443
• HGNCID: 12718
• Length: 422
• Species: Homo sapiens
• Sequence 2: NP_608697.1
• Gene: CG9962 / 33448
• FlyBaseID: FBgn0031441
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 97/340 - (28%)
• Similarity: 152/340 - (44%)
• Gaps: 68/340 - (20%)

Human    45 IGQGGFGCIYLADMNSSESVGSDAPCVVKVEPSDNGP--LFTELKFYQRAAKPEQIQKWIRTRKL 107
            :|.|.||.||     .::.:||.....:|||..:.|.  |..|...|               ..|
  Fly    21 LGSGSFGDIY-----EAKHMGSGLHVALKVERKNAGQSHLSIESTVY---------------NLL 65

Human   108 KY-LGVP---KYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILE 168
            :: :|:|   :::.:..||       .::|:..|..|:.::....:|||.||||.|:.:::|.||
  Fly    66 RHGMGIPMTYQFFSNRRHD-------VLVMELLGPSLETLFTMCNRRFSMKTVLMLADQMVDRLE 123

Human   169 YIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHD---GTIEF 229
            |:|.|.|||.|||..|.|:.. ....:::|:|:||:.||..   .||.:..|:|...   ||..:
  Fly   124 YLHLHHYVHRDIKPENFLMGVGLTRHRLHLIDFGLSKRYWD---MKENRHVPQRRGTKWAGTARY 185

Human   230 TSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPE 294
            .|::|......|||.|||.:||.:|..|.|.|||:..|.      :||::..|.|..:.....|.
  Fly   186 ASVNALCCKVQSRRDDLESVGYVLIYLLRGSLPWQGLLP------NSKLQKAEMILEMKLSTLPN 244

Human   295 K---NKPGEIAKYMETVKLLDYTEKPLYENLRDI---LLQGLKAI---------GSKDDGKLDLS 344
            .   ..|.|...|:...:.|.:.|:|.|..:|..   ||..||..         ..|:.||
  Fly   245 SLCAGYPNEFYNYIIYTRQLGFEEEPDYRMIRCTFLSLLFNLKFTNDLIYDWDHAEKNSGK---- 305

Human   345 VVENGGLKAKTITKK 359
               :|..:.:.:.||
  Fly   306 ---SGSEEDRVVVKK 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VRK1	XP_047287708.1	STKc_VRK1	28..328	CDD:271024	88/298 (30%)
CG9962	NP_608697.1	STKc_CK1	17..279	CDD:270918	87/293 (30%)