DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rnf145 and rnf145a

DIOPT Version :9

Sequence 1:NP_001350095.1 Gene:Rnf145 / 74315 MGIID:1921565 Length:663 Species:Mus musculus
Sequence 2:XP_005157379.1 Gene:rnf145a / 565986 ZFINID:ZDB-GENE-111012-3 Length:649 Species:Danio rerio


Alignment Length:641 Identity:538/641 - (83%)
Similarity:581/641 - (90%) Gaps:10/641 - (1%)


- Green bases have known domain annotations that are detailed below.


Mouse     1 MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLNNNPLFQYKYLALNMHYVGYIL 65
            ||.||::||||||.|||||||||:||||||||||||:|||||||||||||||||||.:|||||||
Zfish     1 MAVKERVEAVLNVGLRVPSIMLLEVLYRWDVSSFFQKIQRSSLNNNPLFQYKYLALYLHYVGYIL 65

Mouse    66 SVVLLTLPRQHLVQLYLYFVTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQ 130
            |:||||||||||||||||.:|||||:||||||||||||||||.||||:||||||:|||||||:.|
Zfish    66 SLVLLTLPRQHLVQLYLYVLTALLLFAGHQISRDYVRSELESGYEGPLYLEPLSINRFTTALLCQ 130

Mouse   131 LVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPY 195
            |||||||||||:||:|||||||:|||:||||||||||||.:|:||||||||||:|||.||||||:
Zfish   131 LVVCTLCSCVMQTKRIWLFSAHLLPLVARLCLVPLETIVFVNRFAMIFTGLEVIYFLASNLLVPF 195

Mouse   196 NLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLL 260
            ||||:|||||.||||||||||||||||||||:|||||.|||||||||||:||||||||.||||||
Zfish   196 NLAKTAYRELAQVVEVYGLLALGMSLWNQLVLPVLFMCFWLVLFALQIYTYFSTRDQPTSRERLL 260

Mouse   261 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILA 325
            |||||||||||.||||||||||||||||||||||||||||||||||||..|:||||||:||||||
Zfish   261 FLFLTSIAECCCTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDNTMHRGMTEGITLLILA 325

Mouse   326 VQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   326 VQTGLIELQVIHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390

Mouse   391 VFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVN 455
            ||||||:|||||||||||||||||||||||||||||||.|||||||||.||.||||||||||:||
Zfish   391 VFPAYMSYMICQFFHMDFWLLIIISSSILTSLQVLGTLLIYVLFMVEELRKAPVENMDDVIYWVN 455

Mouse   456 GTYRLLEFVVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIK 520
            ||||||||:|||||||||||||:|||||||||.|:.|||||||||||||||:|||||||||||||
Zfish   456 GTYRLLEFLVALCVVAYGVSETVFGEWTVMGSTIVLIHSYYNVWLRAQLGWQSFLLRRDAVNKIK 520

Mouse   521 SLPVATQEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLP 585
            |||.|:.:||::|||||:||||||.|||||||||.|||||||||||||:||||||..||.||||.
Zfish   521 SLPTASLQQLQQHNDICSICYQDMTSAVITPCSHLFHAGCLKKWLYVQETCPLCHNQLKGSSQLG 585

Mouse   586 GLGTEAAPQ-PPAGAEQNIVLQEGPEPPDHESPPGTGTQEGSGDSSEHINRGSASQ 640
            ....:..|| .||..|::   |:..||.|.||    ..|:...|.|.  .|..||:
Zfish   586 SSSQDVPPQDTPAQPEED---QDPSEPADSES----NLQDLRQDDSS--TRAPASE 632

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rnf145NP_001350095.1 TRC8_N 8..506 CDD:372682 451/497 (91%)
YLYF motif. /evidence=ECO:0000269|PubMed:29374057 81..84 2/2 (100%)
HRD1 <520..627 CDD:227568 64/107 (60%)
RING-H2_RNF145 533..575 CDD:319598 37/41 (90%)
RING-H2 finger (C3H2C3-type) 537..574 CDD:319598 32/36 (89%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 587..663 17/55 (31%)
rnf145aXP_005157379.1 TRC8_N 8..506 CDD:290425 451/497 (91%)
zf-RING_2 535..575 CDD:290367 35/39 (90%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C193143182
Domainoid 1 1.000 914 1.000 Domainoid score I535
eggNOG 1 0.900 - - E1_COG5243
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 1069 1.000 Inparanoid score I1993
OMA 1 1.010 - - QHG46488
OrthoDB 1 1.010 - - D897451at2759
OrthoFinder 1 1.000 - - FOG0006288
OrthoInspector 1 1.000 - - otm30148
orthoMCL 1 0.900 - - OOG6_109881
Panther 1 1.100 - - LDO PTHR22763
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R7680
SonicParanoid 1 1.000 - - X4575
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
ZFIN 1 1.500 - -
1616.300

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