| Sequence 1: | NP_003370.2 | Gene: | EZR / 7430 | HGNCID: | 12691 | Length: | 586 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_648745.1 | Gene: | sstn / 39643 | FlyBaseID: | FBgn0036476 | Length: | 635 | Species: | Drosophila melanogaster |
| Alignment Length: | 292 | Identity: | 56/292 - (19%) |
|---|---|---|---|
| Similarity: | 107/292 - (36%) | Gaps: | 80/292 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Human 275 RINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQ-AREEKHQKQLE---RQQLETEKKRRETVER 335
Human 336 EK--EQMM-----REKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADR 393
Human 394 MAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVK 458
Human 459 TKEELHLVMTAPPPPPPPVYEPV-----SYHVQESLQDEGAEPTGYSAELSSEG--IRDDRNEEK 516
Human 517 RITEAEKNERV-------------QRQLLTLS 535 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| EZR | NP_003370.2 | B41 | 7..206 | CDD:214604 | |
| [IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000305|PubMed:25417112 | 115..120 | ||||
| FERM_C_ERM | 200..296 | CDD:270015 | 5/20 (25%) | ||
| Interaction with SCYL3. /evidence=ECO:0000269|PubMed:12651155 | 244..586 | 56/292 (19%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 306..341 | 11/40 (28%) | |||
| ERM_helical | 337..456 | CDD:466641 | 20/125 (16%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 485..564 | 13/66 (20%) | |||
| ERM_C | 510..586 | CDD:459932 | 7/39 (18%) | ||
| sstn | NP_648745.1 | None | |||
| Blue background indicates that the domain is not in the aligned region. | |||||