| Sequence 1: | NP_001104547.1 | Gene: | EZR / 7430 | HGNCID: | 12691 | Length: | 586 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_727290.1 | Gene: | Moe / 31816 | FlyBaseID: | FBgn0011661 | Length: | 649 | Species: | Drosophila melanogaster |
| Alignment Length: | 645 | Identity: | 340/645 - (52%) |
|---|---|---|---|
| Similarity: | 442/645 - (68%) | Gaps: | 82/645 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Human 3 KPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLHYVDNKGFPTWLKLDKK--- 64
Human 65 --------------------------------------------------VSAQEVRKENPLQFK 79
Human 80 FRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKS 144
Human 145 GYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIK 209
Human 210 NKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRL 274
Human 275 RINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQ 339
Human 340 MMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKR---AQEEAERLEADRMAALRAKE 401
Human 402 ELER-QAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHL 465
Human 466 VMTAPPPPPPPVYEPVSYHVQESLQDEGAEPTG------YSAELSSEGIRDDRNEEKRITEAEKN 524
Human 525 ERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFE 584 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| EZR | NP_001104547.1 | B41 | 7..206 | CDD:214604 | 146/251 (58%) |
| [IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000305|PubMed:25417112 | 115..120 | 4/4 (100%) | |||
| FERM_C_ERM | 200..296 | CDD:270015 | 84/95 (88%) | ||
| Interaction with SCYL3. /evidence=ECO:0000269|PubMed:12651155 | 244..586 | 156/351 (44%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 306..341 | 16/34 (47%) | |||
| ERM | 338..586 | CDD:395622 | 86/257 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 485..564 | 35/84 (42%) | |||
| Moe | NP_727290.1 | B41 | 26..278 | CDD:214604 | 146/251 (58%) |
| FERM_N | 28..83 | CDD:286467 | 44/54 (81%) | ||
| FERM_M | 163..278 | CDD:278785 | 77/114 (68%) | ||
| FERM_C_ERM | 272..368 | CDD:270015 | 84/95 (88%) | ||
| GBP_C | <375..497 | CDD:303769 | 44/132 (33%) | ||
| ERM | 403..649 | CDD:279153 | 88/264 (33%) | ||
| coiled coil | 464..477 | CDD:293879 | 3/12 (25%) | ||
| coiled coil | 486..497 | CDD:293879 | 2/14 (14%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165146928 | |
| Domainoid | 1 | 1.000 | 188 | 1.000 | Domainoid score | I3313 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3529 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 690 | 1.000 | Inparanoid score | I694 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG52274 | |
| OrthoDB | 1 | 1.010 | - | - | D281811at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001629 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41644 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102674 | |
| Panther | 1 | 1.100 | - | - | O | PTHR23281 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4666 |
| SonicParanoid | 1 | 1.000 | - | - | X1031 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.800 | |||||