| Sequence 1: | NP_000542.1 | Gene: | VHL / 7428 | HGNCID: | 12687 | Length: | 213 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001016367.1 | Gene: | vhl / 549121 | XenbaseID: | XB-GENE-493997 | Length: | 167 | Species: | Xenopus tropicalis |
| Alignment Length: | 149 | Identity: | 96/149 - (64%) |
|---|---|---|---|
| Similarity: | 122/149 - (81%) | Gaps: | 2/149 - (1%) |
- Green bases have known domain annotations that are detailed below.
|
Human 55 EAGRPR--PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLW 117
Human 118 LFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVR 182
Human 183 SLYEDLEDHPNVQKDLERL 201 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| VHL | NP_000542.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..65 | 4/11 (36%) | |
| 8 X 5 AA tandem repeats of G-[PAVG]-E-E-[DAYSLE] | 14..53 | ||||
| VHL | 63..144 | CDD:460360 | 50/80 (63%) | ||
| Involved in binding to CCT complex | 100..155 | 31/54 (57%) | |||
| VHL_C | 156..204 | CDD:407332 | 35/46 (76%) | ||
| Interaction with Elongin BC complex | 157..166 | 7/8 (88%) | |||
| vhl | NP_001016367.1 | pVHL | 15..152 | CDD:176472 | 90/136 (66%) |
| Blue background indicates that the domain is not in the aligned region. | |||||