DRSC/TRiP Functional Genomics Resources

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Protein Alignment VHL and erj5

DIOPT Version :10

Sequence 1:NP_000542.1 Gene:VHL / 7428 HGNCID:12687 Length:213 Species:Homo sapiens
Sequence 2:NP_594141.1 Gene:erj5 / 2541520 PomBaseID:SPAC2E1P5.03 Length:303 Species:Schizosaccharomyces pombe


Alignment Length:45 Identity:12/45 - (26%)
Similarity:16/45 - (35%) Gaps:8/45 - (17%)


- Green bases have known domain annotations that are detailed below.


Human    62 VLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTG 106
            :||:..:|:.......|..||     |   .|....|....||.|
pombe    88 ILRNTETRKRYDYFLKNGFPR-----W---KGTGYLYSRYRPGLG 124

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VHLNP_000542.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..65 1/2 (50%)
8 X 5 AA tandem repeats of G-[PAVG]-E-E-[DAYSLE] 14..53
VHL 63..144 CDD:460360 12/44 (27%)
Involved in binding to CCT complex 100..155 3/7 (43%)
VHL_C 156..204 CDD:407332
Interaction with Elongin BC complex 157..166
erj5NP_594141.1 PRK14288 40..>179 CDD:172776 12/45 (27%)
DnaJ 40..99 CDD:395170 3/10 (30%)
Blue background indicates that the domain is not in the aligned region.

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