| Sequence 1: | NP_000542.1 | Gene: | VHL / 7428 | HGNCID: | 12687 | Length: | 213 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_509889.1 | Gene: | vhl-1 / 181321 | WormBaseID: | WBGene00006922 | Length: | 174 | Species: | Caenorhabditis elegans |
| Alignment Length: | 162 | Identity: | 45/162 - (27%) |
|---|---|---|---|
| Similarity: | 67/162 - (41%) | Gaps: | 33/162 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Human 57 GRPRPVL-RSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR 120
Human 121 DAGTHDG--LLVNQTELF----VPSLNVDGQPIFAN---ITLPVYTLKERCLQVVRSLVKPENYR 176
Human 177 RLDIVRSLYEDLEDHPNVQKDLERLTQERIAH 208 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| VHL | NP_000542.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..65 | 4/8 (50%) | |
| 8 X 5 AA tandem repeats of G-[PAVG]-E-E-[DAYSLE] | 14..53 | ||||
| VHL | 63..144 | CDD:460360 | 27/87 (31%) | ||
| Involved in binding to CCT complex | 100..155 | 19/63 (30%) | |||
| VHL_C | 156..204 | CDD:407332 | 8/47 (17%) | ||
| Interaction with Elongin BC complex | 157..166 | 2/8 (25%) | |||
| vhl-1 | NP_509889.1 | pVHL | 19..157 | CDD:176472 | 41/153 (27%) |
| Blue background indicates that the domain is not in the aligned region. | |||||